Results 211 to 220 of about 760,879 (260)

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

open access: yesAdvanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale   +6 more
wiley   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

open access: yesAdvanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li   +7 more
wiley   +1 more source

Materials‐Guided Gene‐Ionizable Lipid Nanoparticles to Reverse Iron‐Associated Immune Resistance in Renal Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Iron overload is a common metabolic disturbance in cancer and contributes to poor outcomes in renal cell carcinoma (RCC), yet its effects on the tumour immune microenvironment remain unclear. Here we identify a previously unrecognized immunosuppressive axis in which iron overload downregulates the palmitoyltransferase ZDHHC12 in CD8+ T cells ...
Xin Jin   +16 more
wiley   +1 more source

Advancing Clinical Research

open access: yes
Advanced Science, EarlyView.
wiley   +1 more source

Herpes simplex virus DNA

Virology, 1968
Abstract Herpes simplex virus DNA was isolated in an intact form by treating the virus particles with detergents. An average molecular weight of 100 × 106 daltons was determined for herpes simplex virus DNA, both by electron microscopy and by zone centrifugation in sucrose gradients.
Y, Becker, H, Dym, I, Sarov
openaire   +2 more sources

Infectivity of visna virus DNA

Virology, 1976
Abstract Deoxyribonucleic acid isolated from cells infected with the RNA containing slow virus visna confers on uninfected cells the capacity to synthesize new virus. The cytopathic agent isolated in these experiments has the biological and biochemical properties of visna virus, and the active material is DNA by several criteria, the most important ...
A T, Haase   +3 more
openaire   +2 more sources

Topography of vaccinia virus DNA

Virology, 1977
Abstract Contour length measurements in an electron microscope of vaccinia genomes released from virions by lysis in Sarkosyl and 2-mercaptoethanol at 4° on the surface of gradients, followed by sedimentation into the gradients to remove proteins, showed that the linear, double-stranded (ds) viral DNA molecules prepared in this way, had a MW of 132 ...
M, Esteban, L, Flores, J A, Holowczak
openaire   +2 more sources

DNA virus maturation

Journal of Cellular Physiology, 1969
Maturation of bacterial viruses requires the formation of mature viral nucleic acid in the form found in progeny virus particles, the “packaging” of this viral nucleic acid within a capsule, and the assembly of “packaged” nucleic acid with the accessory structures necessary for infectivity.
openaire   +3 more sources

Studies on vaccinia virus DNA

Virology, 1967
Abstract A method has been developed for the isolation of intact DNA genomes from purified vaccinia virions. A molecular weight of 150 × 106 to 170 × 106 daltons was determined for vaccinia virus DNA molecules by zone centrifugation and electron microscopy, respectively.
I, Sarov, Y, Becker
openaire   +2 more sources

The Insertion of DNA into Vaccinia Virus

Science, 1976
Cells infected with vaccinia virus in the presence of hydroxyurea (HU), which blocks DNA replication, were examined in thin sections by electron microscopy at intervals after removal of HU. Dense, fibrillar material was observed at the orifice formed just before closure of the membrane constituting the envelope of the immature form of the virus.
openaire   +2 more sources

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