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Infectivity of visna virus DNA
Virology, 1976Abstract Deoxyribonucleic acid isolated from cells infected with the RNA containing slow virus visna confers on uninfected cells the capacity to synthesize new virus. The cytopathic agent isolated in these experiments has the biological and biochemical properties of visna virus, and the active material is DNA by several criteria, the most important ...
A T, Haase +3 more
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DNA vaccination against respiratory influenza virus infection
Vaccine, 2001DNA vaccination using plasmid encoding the hemagglutinin (HA) gene of influenza A/PR/8/34 virus to induce long-lasting protective immunity against respiratory infection was evaluated in this study. Using liposomes as carriers, the efficacy of DNA vaccines was determined using a lethal influenza infection model in mice.
J P, Wong +7 more
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Unstable DNA synthesized by polyoma virus-infected cells
Virology, 1966Confluent mouse embryo monolayer cultures are induced by infection with polyoma virus to synthesize DNA which behaves on columns of methylated albumin and upon band centrifugation like cellular DNA. “Pulse-chase” experiments revealed that this DNA, in contrast to normal cellular DNA, is degraded in the infected cultures to a molecular weight ...
T, Ben-Porat, C, Coto, A S, Kaplan
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Mitochondrial DNA Role in Zika Virus Infection
2022Zika virus (ZIKV) is a member of the Flavivirus family. ZIKV infection ranges from asymptomatic to a mild disease in adults. However, in 2015, ZIKV infection became a public health emergency in the Americas associated with neurological alterations such as Guillain-Barré syndrome (GBS) in adults and congenital zika syndrome (CZS). By blocking type I IFN
Fabiana Rabe Carvalho +2 more
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Mechanisms of DNA virus infection entry and early events
Frontiers in Bioscience, 2002The cellular components engaged in entry of viruses has been an area of intense investigation in recent years. We examine the entry and receptors used for well-studied and prevalent human DNA viruses adenoviruses, poxviruses and two herpesviruses- herpes simplex virus and Epstein-Barr virus. Little is yet known about the entry or early events for other
A Oveta, Fuller, Pilar, Perez-Romero
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Chemotherapy of DNA virus infections
1999Abstract In recent years there have been considerable advances in the development of effective antiviral drugs. Much of this progress has been driven by the need to combat human immunodeficiency virus (HIV) infection, but there are currently nearly thirty antiviral agents in clinical development or licensed for use in humans against DNA ...
Patricia A Cane, Deenan Pillay
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The infectivity of nuclear polyhedrosis virus DNA
Annales de l'Institut Pasteur / Virologie, 1981Summary Trichoplusia ni multiply-enveloped nuclear polyhedrosis virus DNA is infectious provided it is circular and double-stranded. This has been shown by comparing linear, nicked circular (nc) and covalently closed (cc) DNA, with single-stranded derivatives, and by comparing naturally cccurring forms with forms generated enzymatically with ligase
D.C. Kelly, X. Wang
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Virus DNA and host DNA in polyoma virus-infected cells at high temperature
Virology, 1972Abstract Incubation of mouse kidney (MK) cells at 41.6 ± 0.1° led to a rapid inhibition of DNA synthesis. Infection with the SP 2 mutant of polyoma virus (PV) at 41.6° induced the cells to synthesize DNA again. However, production of infectious SP 2 DNA or infectious virions was reduced under these conditions.
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Agrobacterium-mediated infectivity of cloned digitaria streak virus DNA
Virology, 1988A monomeric clone of double-stranded DNA synthesized in vitro DNA of the geminivirus Digitaria streak (DSV) was subcloned as a tandem dimeric unit into a binary vector of Agrobacterium tumefaciens, creating a plasmid pDS2. Inoculation of digitaria sanguinalis with A. tumefaciens carrying pDS2 resulted in viral infection.
J, Donson +6 more
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Aberrant DNA methylation profile of hepatitis B virus infection
Journal of Medical Virology, 2018We aimed to study the aberrant DNA methylation profile associated with hepatitis B virus (HBV) infection and, to identify key genes and pathways associated with the HBV infection stage. A total of 54 antiviral treatment‐naïve HBV‐infected patients and six healthy controls were included.
Jinglan Jin +4 more
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