Results 141 to 150 of about 367,032 (262)

Viral metagenomic analysis of fecal samples from <i>Bos grunniens</i> on the Qinghai-Tibet Plateau reveals novel picornaviruses and diverse CRESS-DNA viruses. [PDF]

Front Cell Infect Microbiol
Chen J, Gong G, Su X, Song X, Zhang J, Wu P, Wang H, Shan T, Zhang W.   +8 more
europepmc   +1 more source

Bacteria and Fungi Synergistically Reprogram Flavonoid Metabolites in the Pericarp of Citrus Reticulata 'Chachi' During Storage

Advanced Science, EarlyView.
The authors employed widely targeted metabolomics, microbial amplicon sequencing, and fermentation assays to investigate the microbiome 's influence on PCRC 's (pericarp of Citrus reticulata ' Chachi ') flavonoid profile over 0–19 years of storage. Based on the correlation analysis, solid‐state and liquid‐state fermentation, and catalytic activity ...
Jianmu Su, Sisheng Zhang, Lidi Liang, Haiyi Bai, Mei Bai, Hanjun He, Yayu Wang, Huan Liu, Xiangxiu Liang, Yu Sun, Hong Wu   +10 more
wiley   +1 more source

Double-stranded DNA viruses may serve as vectors for horizontal transfer of intron-generating transposons. [PDF]

Mob DNA
Gozashti L, Corbett-Detig R.
europepmc   +1 more source

Infection Defects of RNA and DNA Viruses Induced by Antiviral RNA Interference. [PDF]

Microbiol Mol Biol Rev, 2023
Liu S, Han Y, Li WX, Ding SW.
europepmc   +1 more source

Liver Stiffness Directs Intrahepatic Cholesterol Accumulation Through YAP/TAZ in Metabolic Dysfunction‐Associated Steatotic Liver Disease

Advanced Science, EarlyView.
Liver stiffness promotes intrahepatic cholesterol accumulation by repressing LXRα through YAP/TAZ activation. Stiff matrices impair cholesterol efflux in hepatocytes, while YAP/TAZ deletion restores LXRα activity and prevents cholesterol‐induced fibrosis.
Na Young Lee, Myeung Gi Choi, Ho Jae Ryu, Young Jin Min, Seon Min Kim, Yeonseok Chung, Bo Kyung Koo, Yun Pyo Kang, Won Kim, Ja Hyun Koo   +9 more
wiley   +1 more source

Screening great ape museum specimens for DNA viruses. [PDF]

Sci Rep
Hämmerle M, Guellil M, Trgovec-Greif L, Cheronet O, Sawyer S, Ruiz-Gartzia I, Lizano E, Rymbekova A, Gelabert P, Bernardi P, Han S, Rattei T, Schuenemann VJ, Marques-Bonet T, Guschanski K, Calvignac-Spencer S, Pinhasi R, Kuhlwilm M.   +17 more
europepmc   +1 more source

Large-scale invasion of unicellular eukaryotic genomes by integrating DNA viruses. [PDF]

Proc Natl Acad Sci U S A, 2023
Bellas C, Hackl T, Plakolb MS, Koslová A, Fischer MG, Sommaruga R.   +5 more
europepmc   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

Detection of DNA Viruses in Free-Ranging Rat Populations in Hungary. [PDF]

Viruses
Vidovszky MZ, Surján A, Földvári G, Egyed L.   +3 more
europepmc   +1 more source

CypD Dependent mPTP Opening Is Crucial for Oxidized Mitochondrial DNA Release in Ferroptosis

Advanced Science, EarlyView.
Ferroptosis is driven by mitochondrial permeability transition pore (mPTP) opening, which induces mitochondrial swelling and releases oxidized mitochondrial DNA. The released mtDNA activates cGAS–STING signaling, promotes ferritinophagy, and amplifies ferroptotic cell death. Disruption of mtDNA repair sensitizes tumors to ferroptosis in vivo, revealing
Hong Zhou, Wan Fu, Shizuo Liu, Zili Zhang, Hanyan Luo, Qing Zhong   +5 more
wiley   +1 more source