Results 111 to 120 of about 8,074 (224)

DNAzyme‐Based Nanostructures for Dynamic Cell Regulation and Sensing

ChemistryOpen
This review systematically explores the cutting‐edge advancements in DNAzyme‐based nanostructures for dynamic cellular regulation and biosensing. As catalytic DNA molecules, DNAzymes exhibit high stability, programmability, and versatile functionality ...
Haoyu Fan, Xichen Du, Ruocan Qian
doaj   +1 more source

Colorimetric and electrochemical analysis of DNAzyme-LAMP amplicons for the detection of Escherichia coli in food matrices

Scientific Reports
Foodborne bacteria like Escherichia coli threaten global food security, necessitating affordable, on-site detection methods, especially in resource-limited settings.
Alaa H. Sewid, Haley C. Dylewski, Joseph H. Ramos, Bailey M. Morgan, Benti D. Gelalcha, Doris H. D’Souza, Jie Jayne Wu, Oudessa Kerro Dego, Shigetoshi Eda   +8 more
doaj   +1 more source

Calcium-Dependent Chemiluminescence Catalyzed by a Truncated c-MYC Promoter G-Triplex DNA

Molecules
The dynamic landscape of non-canonical DNA G-quadruplex (G4) folding into G-triplex intermediates has led to the study of G-triplex structures and their ability to serve as peroxidase-mimetic DNAzymes.
Malay Kumar Das, Elizabeth P. Williams, Mitchell W. Myhre, Wendi M. David, Sean M. Kerwin   +4 more
doaj   +1 more source

Detection of antibiotic-resistance genes in bacterial pathogens using a Cas12a/3D DNAzyme colorimetric paper sensor

Fundamental Research
The rapid detection of antibiotic-resistant genes in bacterial pathogens is critical in combating global health crises. Herein, we report a CRISPR/Cas12a-based colorimetric paper sensor, where the trans-cleavage activity of Cas12a was post-amplified by ...
Hua Gao, Yanan Li, Yaqiong Li, Ke Qu, Kaixiang Zhang, Jinghong Li   +5 more
doaj   +1 more source

3D DNAzyme Motor Nanodevice With Self‐Powered FRET Amplifier and Self‐Supplied H2O2 for Enhancing Human Neutrophil Elastase Profiling and Chemodynamic Therapy in Lung Tumor

Advanced Science
The development of theragnostic nanosystems integrating FRET (fluorescence resonance energy transfer) imaging and chemodynamic therapy (CDT) for accurate diagnosis and effective treatment of lung tumors is still a big challenge.
Huiyan Du, Ensheng Xu, Yihan Xu, Qingwang Xue, Hongxia Xu, Jibin Song   +5 more
doaj   +1 more source

Use of DNAzymes for cancer research and therapy [PDF]

, 2012

core   +1 more source

ゾル−ゲル転移を示す生体適合ポリマー材料の開発と応用 (2) [PDF]

, 2019
(1) Title: Bulk pH Responsive DNA Quadruplex Hydrogels Prepared by Liquid-Phase Large Scale DNA SynthesisJournal: ACS Macro Letters(2) Title: Communication—DNA Quadruplex Hydrogel Beads Showing Peroxidase ActivityJournal: Journal of The Electrochemical ...
Fukushima Kazuki, Kuzuya Akinori, Ohya Yuichi, Soo Khim Chan, Tanaka Shizuma, Theam Soon Lim, Wakabayashi Kenta, Yukami Shinsuke, 大矢 裕一, 田中 静磨, 葛谷 明紀   +10 more
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Cascaded and autocatalytic dumbbell probe for exponentially amplified and label-free highly-sensitive fluorescent biosensing of miRNA from cancer cells

Sensors and Actuators Reports
miRNAs are valuable biomarkers for cancer diagnostics, but their low abundance and miRNAs are valuable biomarkers for cancer diagnostics, but their low abundance and sequence similarity pose challenges for reliable detection.
Min Zhong, Nianting Xiao, Yaqin Tang, Yu Liu, Xiao Guo, Chunyuan Gan, Wenli Wu, Lian Yi, Daxiu Li   +8 more
doaj   +1 more source

Bioinformatics designing of 10-23 deoxyribozyme against noncoding region before start codon of beta-galactosidase gene (lacZ) in pGEM-T vector [PDF]

, 2018
Background and aims: Deoxyribozymes are oligoribodeoxynucleotides that catalyze reactions such as cutting RNA and have diagnostic and therapeutic applications. Deoxyribozyme 10-23 includes a catalytic domain dependent on a fixed 15-nucleotic (mer) cation
Esmaeili, Abolghasem., Javadi Zarnaghi, Fatemeh., Sadeghi, Sanaz.   +2 more
core  

Analysis of TX-100 based microemulsion in the presence of TB drug isoniazid [PDF]

, 2011
The present study delineate the formulation of microemulsion composed of TX-100:AcOH(1:1), Chloroform, Water and to investigate its potential as drug delivery system for an antitubercular drug isoniazid. The pseudo-ternary phase diagram (Gibbs Triangle)
Kumar, Shailesh
core