Results 1 to 10 of about 517,159 (303)
Nanobioconjugates for Signal Amplification in Electrochemical Biosensing [PDF]
Molecules, 2020 Nanobioconjugates are hybrid materials that result from the coalescence of biomolecules and nanomaterials. They have emerged as a strategy to amplify the signal response in the biosensor field with the potential to enhance the sensitivity and detection ...
Sebastian Cajigas, Jahir Orozco
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Thermodynamically Driven Signal Amplification [PDF]
CoRR, 2023 The field of chemical computation attempts to model computational behavior that arises when molecules, typically nucleic acids, are mixed together. Thermodynamic binding networks (TBNs) is a highly abstracted model that focuses on which molecules are bound to each other in a "thermodynamically stable" sense. Stability is measured based only on how many
Joshua Petrack +2 more
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Microcapsule-Based Signal Amplification Method for Biomolecules
Sensors, 2019 The direct signal amplification of target molecules could be an effective means of increasing the sensitivity and reducing the size of biosensors. The purpose of this study was to propose a novel signal amplification method suitable for the detection of ...
Masaki Yamaguchi
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Cleavage-based signal amplification of RNA [PDF]
Nature Communications, 2013 RNA detection has become an integral part of current biomedical research. Up to now, the reverse transcription-PCR has been the most practical method to detect mRNA targets. However, RNA detection by reverse transcription-PCR requires sophisticated equipment and it is highly sensitive to contamination with genomic DNA.
Yongyun, Zhao, Li, Zhou, Zhuo, Tang
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Magnetic micro/nanoparticle flocculation-based signal amplification for biosensing
International Journal of Nanomedicine, 2016 Omary Mzava,1 Zehra Tas,1 Kutay İçöz1,2 1BioMINDS (Bio Micro/Nano Devices and Sensors) Laboratory, Department of Electrical and Electronics Engineering, 2Bioengineering Department, Abdullah Gül University, Kayseri, Turkey Abstract: We ...
Mzava O, Taş Z, İçöz K
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Review of Microchip Analytical Methods Coupled with Aptamer-Based Signal Amplification Strategies for High-Sensitivity Bioanalytical Applications [PDF]
BiosensorsAptamers have many advantages, including facile synthesis and a high affinity and good selectivity toward their targets. Therefore, aptamer-based biosensors have become increasingly popular for the detection of different bioanalytical substances ...
Xudong Xue +3 more
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DNA origami signal amplification in lateral flow immunoassays [PDF]
Nature CommunicationsLateral flow immunoassays (LFIAs) enable a rapid detection of analytes in a simple, paper-based test format. Despite their multiple advantages, such as low cost and ease of use, their low sensitivity compared to laboratory-based testing limits their use ...
Heini Ijäs +6 more
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Application of nucleic acid signal amplification in biosensing and bioimaging
Biomedical TechnologyNucleic acid amplification techniques are broadly employed in nucleic acid testing due to their efficient accumulation of nucleic acid sequences. With the development of biotechnology, they are further applied to proteins, living cells, extracellular ...
Junqi Zhao +3 more
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Frontiers in Chemistry, 2022 The field of infectious disease diagnostics is burdened by inequality in access to healthcare resources. In particular, “point-of-care” (POC) diagnostics that can be utilized in non-laboratory, sub-optimal environments are appealing for disease control ...
Xingcheng Zhou +4 more
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Glial amplification of synaptic signals [PDF]
The Journal of Physiology, 2021 Key points Recent studies have repeatedly demonstrated the cross‐talk of heterogeneous signals between neuronal and glial circuits. Here, we investigated the mechanism and the influence of physiological interactions between neurons and ...
Kaoru Beppu, Naoko Kubo, Ko Matsui
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