Results 1 to 10 of about 6,973,238 (322)

Novel Signal Amplification Technology with Applications in DNA and Protein Detection Systems

open access: yesBioTechniques, 2001
A non-enzymatic approach to signal amplification has practical advantages over conventional target amplification methods. We have designed a simple, cost-efficient signal amplification system that can be used to enhance the detection of nucleic acids or ...
C.M. Lisle   +4 more
doaj   +1 more source

Nanobioconjugates for Signal Amplification in Electrochemical Biosensing

open access: yesMolecules, 2020
Nanobioconjugates are hybrid materials that result from the coalescence of biomolecules and nanomaterials. They have emerged as a strategy to amplify the signal response in the biosensor field with the potential to enhance the sensitivity and detection ...
Sebastian Cajigas, Jahir Orozco
doaj   +1 more source

Signal amplification in a qubit-resonator system [PDF]

open access: yes, 2015
We study the dynamics of a qubit-resonator system, when the resonator is driven by two signals. The interaction of the qubit with the high-amplitude driving we consider in terms of the qubit dressed states.
Astafiev O.   +6 more
core   +2 more sources

MiRNA Detection Using a Rolling Circle Amplification and RNA-Cutting Allosteric Deoxyribozyme Dual Signal Amplification Strategy

open access: yesBiosensors, 2021
A microRNA (miRNA) detection platform composed of a rolling circle amplification (RCA) system and an allosteric deoxyribozyme system is proposed, which can detect miRNA-21 rapidly and efficiently.
Chenxin Fang   +7 more
doaj   +1 more source

Precision spectroscopy by photon-recoil signal amplification [PDF]

open access: yes, 2014
Precision spectroscopy of atomic and molecular ions offers a window to new physics, but is typically limited to species with a cycling transition for laser cooling and detection.
Amairi, Sana   +9 more
core   +3 more sources

A Fluorescence Assay for Exosome Detection Based on Bivalent Cholesterol Anchor Triggered Target Conversion and Enzyme-Free Signal Amplification.

open access: yesAnalytical Chemistry, 2021
Exosomes are emerging as one of the most promising biomarkers for early disease diagnosis and prognosis. The significant challenges facing the available methods include improving the detection specificity and sensitivity in complex biological samples ...
Xiaokun Wang   +3 more
semanticscholar   +1 more source

Signal Amplification by Sensitive Control of Bifurcation Topology [PDF]

open access: yes, 2011
We describe a novel amplification scheme based on inducing dynamical changes to the topology of a bifurcation diagram of a simple nonlinear dynamical system.
Cross, M. C.   +5 more
core   +1 more source

Signal amplification by rolling circle amplification on DNA microarrays [PDF]

open access: yesNucleic Acids Research, 2001
While microarrays hold considerable promise in large-scale biology on account of their massively parallel analytical nature, there is a need for compatible signal amplification procedures to increase sensitivity without loss of multiplexing. Rolling circle amplification (RCA) is a molecular amplification method with the unique property of product ...
G, Nallur   +9 more
openaire   +2 more sources

Amplification Characteristics of a Coumarin 460-Based Tunable Amplifier

open access: yesIEEE Photonics Journal, 2020
We studied the optical signal amplification properties of coumarin 460 (C460) in solution. An optical signal amplification experiment was performed using a side-pumping setup.
Jianping Shen, Wei Wang, Siwei Zhang
doaj   +1 more source

SARS-CoV-2 RNA Detection with Duplex-Specific Nuclease Signal Amplification

open access: yesMicromachines, 2021
The emergence of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a zoonotic pathogen, has led to the outbreak of coronavirus disease 2019 (COVID-19) pandemic and brought serious threats to public health worldwide.
Meiqing Liu   +4 more
doaj   +1 more source

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