Results 41 to 50 of about 6,973,238 (322)

Short review: Electrochemical MicroRNAs Biosensors Based on Enzymatic Signal Amplification

International Journal of Electrochemical Science, 2015
Recently, microRNAs (miRNAs) have been considered as reliable molecular biomarkers for early diagnosis of various diseases because their aberrant expression has been correlated with cardiovascular, diabetes, tissue injury and cancer.
Xiao-Yang Zhao, Wei Liu, Bin-Bin Zhou, Shan-Shan Liu, Guo-Cheng Han   +4 more
doaj   +1 more source

Can Anomalous Amplification be Attained Without Postselection? [PDF]

, 2016
We present a parameter estimation technique based on performing joint measurements of a weak interaction away from the weak-value-amplification approximation.
Howell, John C., Liu, Wei-Tao, Martínez-Rincón, Julián, Viza, Gerardo I.   +3 more
core   +3 more sources

Microwave amplification with nanomechanical resonators

, 2011
Sensitive measurement of electrical signals is at the heart of modern science and technology. According to quantum mechanics, any detector or amplifier is required to add a certain amount of noise to the signal, equaling at best the energy of quantum ...
AA Clerk, AD O’Connell, AH Safavi-Naeini, AJ Leggett, B Yurke, C Genes, CA Regal, CH Metzger, CM Caves, D Rugar, DW Carr, F Marquardt, F. Massel, H. Saloniemi, HA Haus, I Wilson-Rae, J Sulkko, J.-M. Pirkkalainen, JD Teufel, JD Teufel, JP Raskin, M. A. Sillanpää, MA Castellanos-Beltran, MA Sillanpää, MJ Woolley, MO André, N Bergeal, O Arcizet, P. J. Hakonen, S Mancini, S Weis, S. U. Cho, T Rocheleau, T. T. Heikkilä, TJ Kippenberg, VB Braginsky, W Marshall   +36 more
core   +1 more source

Negative optical inertia for enhancing the sensitivity of future gravitational-wave detectors [PDF]

, 2010
We consider enhancing the sensitivity of future gravitational-wave detectors by using double optical spring. When the power, detuning and bandwidth of the two carriers are chosen appropriately, the effect of the double optical spring can be described as ...
Chunnong Zhao, Farid Khalili, Haixing Miao, Helge Müller-Ebhardt, P. Fritschel, Stefan Danilishin, V. B. Braginsky, V. B. Braginsky, W. G. Unruh, Yanbei Chen   +9 more
core   +2 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Application of nucleic acid signal amplification in biosensing and bioimaging

Biomedical Technology
Nucleic acid amplification techniques are broadly employed in nucleic acid testing due to their efficient accumulation of nucleic acid sequences. With the development of biotechnology, they are further applied to proteins, living cells, extracellular ...
Junqi Zhao, Xueqin Li, Dagan Zhang, Sen Wang   +3 more
doaj   +1 more source

Optical parametric amplification and oscillation assisted by low-frequency stimulated emission

, 2016
Optical parametric amplification/oscillation provide a powerful tool for coherent light generation in spectral regions inaccessible to lasers. Parametric gain is based on a frequency {\it down-conversion} process, and thus it can not be realized for ...
Longhi, Stefano
core   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Optimal Probe Wavefunction of Weak-Value Amplification

, 2012
The weak measurement proposed by Aharonov and his colleagues extracts information of a physical quantity of the system by the post selection as the shifts of the argument of the probe wavefunction. The shift is called the weak value and is larger for the
Hosoya, Akio, Shikano, Yutaka, Susa, Yuki   +2 more
core   +1 more source

Continuous phase amplification with a Sagnac interferometer [PDF]

, 2009
We describe a weak value inspired phase amplification technique in a Sagnac interferometer. We monitor the relative phase between two paths of a slightly misaligned interferometer by measuring the average position of a split-Gaussian mode in the dark ...
Dixon, P. Ben, Howell, John C., Jordan, Andrew N., Starling, David J., Williams, Nathan S.   +4 more
core   +3 more sources