Results 91 to 100 of about 1,137,951 (298)
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
A Clinical Study Evaluating Posttraumatic Consequences in Permanent Teeth
Česká Stomatologie a Praktické Zubní Lékařství, 2006 Injuries of permanent teeth belong to the most frequent traumas of the oro-facial region. Hard and periodontal tissues and the pulp of the tooth can be involved.
H. Hecová +2 more
doaj
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Verification of Validity of Caries Measuring by Laser Fluorescent Apparatus KaVo DIAGNOdent
Česká Stomatologie a Praktické Zubní Lékařství, 2005 The authors decide to evaluate the results of measuring by laser fluorescence apparatus DIAGNOdent (KaVo) in the in vitro experiment. 100 occlusal surfaces of extracted lower and upper third molars, which communicated with oral cavity before extractions,
S. Ságlová +3 more
doaj
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Reaction of Dental Pulp after Fracture of a Clinical Crown of Permanent Teeth
Česká Stomatologie a Praktické Zubní Lékařství, 2006 Fractures of the tooth crown of permanent teeth belong to the most frequent dental injuries. The injury often affects hard dental tissues in complicated fractures, where the fracture line reached into dental pulp, affects dental pulp at well.
H. Hecová +2 more
doaj
, 2014 Les BU de Lyon 2 proposent un nouveau RDV à leurs publics : un atelier de 45 minutes, ouvert à tous, les mardis à partir du 11/02. L'Atelier Doc sera un moment d'échanges et de découverte des outils documentaires.
Magali Romaggi
core
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Environmental education programmes offered by delta environmental centre: Some research findings
Southern African Journal of Environmental Education, 1997 Environmental education has developed over time in South Africa with environmental education centres playing a significant role. However not enough is known about how such centres operate.
Doc Shongwe
doaj