Results 111 to 120 of about 1,137,951 (298)
Dental Treatment in Children under General Anaesthesia
The caries experience of pre-school children has been increasing over the last years. The defects of primary teeth are often so extensive that multiple extractions are necessary. Most of these patients are unable to cooperate due to low age and extend of
R. Ivančaková +2 more
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CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Evaluation of Root Fractures of the Permanent Teeth
Root fractures of the permanent teeth belong to the most severe dental injuries. They usually result from a horizontal impact and the most common afflicted teeth are upper frontal teeth, less common the lower teeth. All tissues of the tooth are afflicted,
H. Hecová, J. Stehlíková
doaj
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Clinical Evaluation of Facet Materials in Fixed Prosthodontics (Part.1)
The aim and purpose of this study was to evaluate the long-term stability of facet crowns, the changes of facet surface, marginal adaptation, cracks or breakage of material, change of shape and colour as well as gingival status and finally the search for
A. Boldaji, E. Cimbura
doaj
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