Results 131 to 140 of about 1,936,753 (303)
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Volume 32, Number 4 - May 1953 [PDF]
, 1953 Volume 32, Number 4 - May 1953. 33 pages including covers and advertisements. Editorial Griffin, Phil, Doc and The Kid Hoye, Robert E., The Immortal Father Paul Martiska, John, Philosophy is Not Afternoon Tea Kelly, Edward, Commended ...
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Dental Treatment in Children under General Anaesthesia
Česká Stomatologie a Praktické Zubní Lékařství, 2008 The caries experience of pre-school children has been increasing over the last years. The defects of primary teeth are often so extensive that multiple extractions are necessary. Most of these patients are unable to cooperate due to low age and extend of
R. Ivančaková +2 more
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Efficacy of Removal of CCL Viruses under Enhanced Coagulation Conditions [PDF]
, 2007 The focus of coagulation as a water treatment process is shifting to accommodate recent regulatory additions that strive to balance the risks between microbial and chemical contamination of drinking water.
Abbaszadegan, Morteza +3 more
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Internal Granuloma - Present State of the Problem
Česká Stomatologie a Praktické Zubní Lékařství, 2007 It has been generally acknowledged that internal granuloma (internal resorption, granuloma internum) originates on the basis of disorder of pulp metabolism, associated with degenerative processes, which follow to chronic inflammation of tooth pulp.The ...
J. Netolický, E. Záhlavová
doaj
Alaska Offender Profile: Adult Probation/Parole, 2002–2012 [PDF]
, 2013 This fact sheet presents data on characteristics of offenders under the supervision of the Alaska Department of Corrections, Division of Probation and Parole (DOC-PP) for the period 2002–2012, and briefly describes how probation and parole operate in ...
Myrstol, Brad A.
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