Results 101 to 110 of about 1,936,753 (303)

ULOGA FABRIKE „BRATSTVO“ U RAZVOJU NOVOG TRAVNIKA//THE ROLE OF THE FACTORY „BRATSTVO“ (BROTHERHOOD) IN THE DEVELOPMENT OF NOVI TRAVNIK [PDF]

open access: yesHistorijski pogledi, 2020
The establishment of the socialist regime had led to thorough political, economic, social, cultural and other changes in Bosnia and Herzegovina. The first decade after the Second World War was marked by the reconstruction of the war-torn country, and ...
Mirza Džananović
doaj  

The Fishes of the streams tributary to Monterey Bay, California [PDF]

open access: yes, 1912
Extract: Bull. Bureau of Fisheries. v. 32, 1912. Doc.
Snyder, John Otterbein
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Are We Able to Take Care of Our Own Dentition? Results of Examination of Oral Hygiene in the High-School Population

open access: yesČeská Stomatologie a Praktické Zubní Lékařství, 2005
The authors refer to clinical survey performed among high school students. The aim of this study was to evaluate the quality of home oral care. Set of 316 students were examined with questionnaire and clinically. Almost all of them suffer from gingivitis.
P. Závodský   +3 more
doaj  

‘What's up, doc?’ [PDF]

open access: yesEuropean Journal of General Practice, 2010
In this first issue of 2010, the European Journal of General Practice continues its series on the ‘Research Agenda for General Practice/Family Medicine and Primary Health Care in Europe’.
openaire   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Oral Hygiene and Orthodontia: What Kind of Approach?

open access: yesČeská Stomatologie a Praktické Zubní Lékařství, 2007
The objective was to determine to what extent the attachment of fixed orthodontic appliance enables oral hygiene in the patient and to summarize possible risks ensuing from insufficient oral hygiene and their impact on hard and soft tissues of oral ...
R. Tichá, J. Tichý, H. Böhmová
doaj  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Anatomical Deviations of Endodontium as a Cause of Failure of Endodontic Treatment

open access: yesČeská Stomatologie a Praktické Zubní Lékařství, 2007
Anatomical conditions in the system of root canals represent a significant factor, which can influence the success of endodontic treatment. The structure and anatomy of endodontium is very complex and differs significantly in individual teeth.
H. Hecová, J. Stehlíková, V. Mašek
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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