Results 171 to 180 of about 2,926,121 (366)

Fabrication of a Lipopolysaccharide‐Targeting Peptide‐Based Colloid for Alleviating Carbapenem‐Resistant Enterobacteriaceae‐Induced Cutaneous Infection

Advanced Healthcare Materials, EarlyView.
In this study, a novel cationic peptide, IW is designed and synthesized, with a tandem‐repeat sequence demonstrating potent activities against a broad spectrum of clinically relevant Carbapenem‐resistant Enterobacteriaceae in both the planktonic and biofilm states. IW is then formulated with P407 to form IW‐P407 colloids.
Ping Zeng, Xinyi Ding, Chenyu Liu, Sheng Chen, Kin‐Fai Chan, Sharon Shui Yee Leung   +5 more
wiley   +1 more source

Super‐Resolution Goes Viral: T4 Virus Particles as Versatile 3D‐Bio‐NanoRulers

Advanced Materials, Volume 37, Issue 12, March 26, 2025.
Various super‐resolution fluorescence microscopy methods achieve nanoscale resolution, vital for visualizing subcellular structures. Choosing suitable biological standards is challenging, demanding precise geometry and specific labeling capabilities. Utilizing T4 bacteriophage as a 3D‐Bio‐NanoRuler is proposed.
José Ignacio Gallea, Oleksii Nevskyi, Zuzanna Kaźmierczak, Ivan Gligonov, Tao Chen, Paulina Miernikiewicz, Anna M. Chizhik, Lenny Reinkensmeier, Krystyna Dąbrowska, Mark Bates, Jörg Enderlein   +10 more
wiley   +1 more source

Smiles2Dock: an open large-scale multi-task dataset for ML-based molecular docking [PDF]

arXiv
Docking is a crucial component in drug discovery aimed at predicting the binding conformation and affinity between small molecules and target proteins. ML-based docking has recently emerged as a prominent approach, outpacing traditional methods like DOCK and AutoDock Vina in handling the growing scale and complexity of molecular libraries. However, the
arxiv  

Radiation mitigation of the intestinal acute radiation injury in mice by 1-[(4-nitrophenyl)sulfonyl]-4-phenylpiperazine. [PDF]

, 2020
The objective of the study was to identify the mechanism of action for a radiation mitigator of the gastrointestinal (GI) acute radiation syndrome (ARS), identified in an unbiased high-throughput screen.
Alli, Claudia, Bhat, Kruttika, Cheng, Fei, Duhachek-Muggy, Sara, Eghbali, Mansoureh, He, Ling, Medina, Paul, Muthukrishnan, Sree Deepthi, Pajonk, Frank, Ruffenach, Gregoire, Saki, Mohammad, Vlashi, Erina   +11 more
core   +1 more source

Materials, Structure, and Interface of Stretchable Interconnects for Wearable Bioelectronics

Advanced Materials, EarlyView.
Stretchable interconnects are one of the fundamental components in achieving robust wearable devices, but their importance is often overlooked. This review highlights their importance and provides insightful information on various materials, configurations, and manufacturing approaches being studied for interconnects.
Yue Li, Asmita Veronica, Jiahao Ma, Hnin Yin Yin Nyein   +3 more
wiley   +1 more source

Mechanism of action of VP1-001 in cryAB(R120G)-associated and age-related cataracts [PDF]

, 2019
PurposeWe previously identified an oxysterol, VP1-001 (also known as compound 29), that partially restores the transparency of lenses with cataracts. To understand the mechanism of VP1-001, we tested the ability of its enantiomer, ent-VP1-001, to bind ...
Andley, Usha P., Covey, Douglas F., Dunyak, Bryan M., Gestwicki, Jason E., Hamilton, Paul D., Izrayelit, Yevgeniy, Makley, Leah N., McGlasson-Naumann, Brittney, Molnar, Kathleen S., Qian, Mingxing, Su, Bonnie   +10 more
core   +2 more sources

Covalent Organic Frameworks for Photocatalysis

Advanced Materials, EarlyView.
This review provides an overview of recent advances in covalent organic frameworks (COFs) for photocatalysis, focusing on sustainable energy applications like water splitting, hydrogen peroxide generation, and CO2 and N2 reduction. It discusses design principles, structure‐function relationships, challenges in COF photocatalysis, and strategies to ...
Bikash Mishra, Akhtar Alam, Avanti Chakraborty, Bidhan Kumbhakar, Samrat Ghosh, Pradip Pachfule, Arne Thomas   +6 more
wiley   +1 more source

DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications

Advanced Materials, EarlyView.
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding, Bing Liu, Andreas Peil, Sisi Fan, Jie Chao, Na Liu   +5 more
wiley   +1 more source

Tail docking in pigs: acute physiological and behavioural responses

Animal, 2008
Tail docking of piglets is a routine procedure on farms to control tail-biting behaviour; however, docking can cause an acute stress response. The objectives of this research were to determine the stress responses to tail docking in piglets and to ...
M.A. Sutherland, P.J. Bryer, N. Krebs, J.J. McGlone   +3 more
doaj  

Saliency based Semi-supervised Learning for Orbiting Satellite Tracking [PDF]

arXiv, 2019
The trajectory and boundary of an orbiting satellite are fundamental information for on-orbit repairing and manipulation by space robots. This task, however, is challenging owing to the freely and rapidly motion of on-orbiting satellites, the quickly varying background and the sudden change in illumination conditions.
arxiv