Results 11 to 20 of about 2,947,274 (350)

Integrated Network Pharmacology, Molecular Docking and Animal Experiment to Explore the Efficacy and Potential Mechanism of Baiyu Decoction Against Ulcerative Colitis by Enema

open access: goldDrug Design, Development and Therapy, 2023
Yuan Cui,1,2 Jingyi Hu,2 Yanan Li,1,2 Ryan Au,1,2 Yulai Fang,2 Cheng Cheng,1 Feng Xu,1,2 Weiyang Li,1,2 Yuguang Wu,1,2 Lei Zhu,2 Hong Shen2 1Nanjing University of Chinese Medicine, Nanjing, People’s Republic of China; 2Affiliated Hospital of Nanjing ...
Cui Y   +10 more
doaj   +6 more sources

Improving survival, growth rate, and animal welfare in piglets by avoiding teeth shortening and tail docking [PDF]

open access: greenJournal of Veterinary Behavior, 2012
Piglets are subjected to several painful procedures during their first week of life, including ear tagging, teeth clipping or grinding (although routinely prohibited in Europe), tail docking (although routinely prohibited in Europe), needle injections (vaccination and iron injection), and castration might be performed for male piglets.
Sanne Van Beirendonck   +5 more
semanticscholar   +4 more sources

Integrated network pharmacology, molecular docking, and animal experiments to reveal the potential mechanism of hesperetin on COPD

open access: goldScientific Reports
Hesperetin (HE), a natural flavonoid exhibiting anti-inflammatory and antioxidant properties, holds significant potential in treating chronic obstructive pulmonary disease (COPD).
Jingxi Wang   +8 more
doaj   +4 more sources

Sedative-hypnotic-like effect and molecular docking of di-naphthodiospyrol from Diospyros lotus in an animal model

open access: closedBiomedicine & Pharmacotherapy, 2017
Diospyros lotus Linn commonly known as date-plum, or Caucasian persimmon has multiple uses in folk medicine. Various parts of this plant is used for alleviating lumbago, dysponea, hemorrhage, insomnia, and hiccup. The plant extracts possess a variety of biological activities, such as anti-inflammatory, sedative, febrifuge, anti-microbial, vermifuge ...
Abdur Rauf   +11 more
semanticscholar   +4 more sources

Molecular docking studies on α-amylase inhibitory peptides from milk of different farm animals [PDF]

open access: goldJournal of Dairy Science, 2023
Milk-derived peptides have emerged as a popular mean to manage various lifestyle disorders such as diabetes. Fermentation is being explored as one of the faster and efficient way of producing peptides with antidiabetic potential. Therefore, in this study, an attempt was made to comparatively investigate the pancreatic α-amylase (PAA) inhibitory ...
Priti Mudgil   +7 more
openalex   +5 more sources

SARS-CoV-2 prevalence in domestic and wildlife animals: A genomic and docking based structural comprehensive review [PDF]

open access: goldHeliyon, 2023
The SARS-CoV-2 virus has been identified as the infectious agent that led to the COVID-19 pandemic, which the world has seen very recently. Researchers have linked the SARS-CoV-2 outbreak to bats for the zoonotic spread of the virus to humans. Coronaviruses have a crown-like shape and positive-sense RNA nucleic acid.
Tuhin Das   +4 more
openalex   +4 more sources

Tail docking and animal welfare [PDF]

open access: greenThe Bovine Practitioner, 2004
Tail docking is a common practice on many dairy farms, and is perceived by many farmers to improve cleanliness and enhance milking parlour efficiency. It is a controversial practice attracting increasing scrutiny by the animal welfare community. Scientific studies have been performed to evaluate physiological and behavioural responses to tail docking ...
P.L. Ruegg
openalex   +3 more sources

Design, Synthesis, Evaluation, and Molecular Docking Study of Ascorbic Acid Dual-Coated Omeprazole Pellets and the Antioxidative Effect of Ascorbic Acid on Omeprazole-Induced Renal Injury in an Animal Model [PDF]

open access: goldACS Omega, 2023
The present study was carried out to investigate the antioxidant effect of ascorbic acid on omeprazole (O.P.)-induced acute kidney infection (AKI). Design of experiment (DoE) was employed to fabricate formulations (P1-P8) by the extrusion spheronization technique, and they were evaluated using various analytical techniques.
Hina Raza   +8 more
openalex   +4 more sources

Molecular docking and anti-ulcerative potential of Cucumis (L. Inodorous) on ibuprofen induced gastric ulceration in male wistar animals

open access: goldBiomedicine & Pharmacotherapy, 2023
The use of NSAIDs have caused stomach injury by inhibiting endogenous mucosal prostaglandin production. Cucumis melo is reported to possess antiulcer potential. This study investigates the mechanism underlying the antiulcer potentials of Cucumis melo (CUM).Thirty-five male Wistar rat were randomly assigned to each of seven groups; A(control given water
Grace I. Adebayo-Gege   +10 more
openalex   +3 more sources

Integration of bioinformatics analysis, molecular docking and animal experiments to study the therapeutic mechanisms of berberine against allergic rhinitis [PDF]

open access: goldScientific Reports
AbstractAllergic rhinitis is a prevalent inflammatory condition that impacts individuals of all age groups. Despite reports indicating the potential of berberine in alleviating allergic rhinitis symptoms, the specific molecular mechanisms and therapeutic targets of berberine remain unclear. This research aims to explore the pharmacological mechanism of
Gaoqing Luo, Ming Gao, Qinghua Lin
openalex   +4 more sources

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