Results 41 to 50 of about 2,947,274 (350)

Purification, Identification and Molecular Docking of Immunomodulatory Peptides from the Heads of Litopenaeus vannamei

Foods, 2022
In order to realize the high-value utilization of Litopenaeus vannamei (L. vannamei) heads, immunomodulatory peptides were prepared from the enzymatic hydrolysate of L.
Weiwei Jiang, Keyu Ren, Zhiyan Yang, Zhou Fang, Yan Li, Xiaoxue Xiang, Yishan Song   +6 more
semanticscholar   +1 more source

Exploring Anti-Nonalcoholic Fatty Liver Disease Mechanism of Gardeniae Fructus by Network Pharmacology, Molecular Docking, and Experiment Validation

ACS Omega, 2022
Gardeniae fructus (GF), the fruit from Gardenia jasminoides Ellis, is a traditional Chinese medicine used for the treatment of nonalcoholic fatty liver disease (NAFLD) in the clinic.
Zhongyan Tang, Lin Li, Zhengxiang Xia
semanticscholar   +1 more source

Clove Flower Extract (Syzygium aromaticum) Has Anticancer Potential Effect Analyzed by Molecular Docking and Brine Shrimp Lethality Test (BSLT)

Veterinary Medicine International, 2022
Various anticancer medications have been discovered due to advances in the health care industry, but they have undesirable side effects. On the other hand, anticancer drugs derived from natural sources have low side effects, making them excellent for ...
E. Aksono, Aprilia Cahya Latifah, L. T. Suwanti, K. U. Haq, Herinda Pertiwi   +4 more
semanticscholar   +1 more source

Network Pharmacology and Molecular Docking-Based Mechanism Study to Reveal Antihypertensive Effect of Gedan Jiangya Decoction

BioMed Research International, 2022
Primary hypertension is understood as a disease with diverse etiology, a complicated pathological mechanism, and progressive changes. Gedan Jiangya Decoction (GJD), with the patent publication number CN114246896A, was designed to treat primary ...
Hanxing Liu, S. A. Mohammed, Fang Lu, Pingping Chen, Yu Wang, Shu-min Liu   +5 more
semanticscholar   +1 more source

In Silico Analysis of Tetrodotoxin Binding in Voltage-Gated Sodium Ion Channels from Toxin-Resistant Animal Lineages

Marine Drugs, 2022
Multiple animal species have evolved resistance to the neurotoxin tetrodotoxin (TTX) through changes in voltage-gated sodium ion channels (VGSCs). Amino acid substitutions in TTX-resistant lineages appear to be positionally convergent with changes in ...
Shana L. Geffeney, Jennie Ann Cordingley, Kenyon Mitchell, Charles T. Hanifin   +3 more
doaj   +1 more source

Harmonization of welfare standards for the protection of pigs with the EU-rules: the case of Croatia [PDF]

, 2009
Three quarters of Croatian pigs are produced in small production units (1-5 sows) and on family farms with mixed farming activities. Only few farms have specialized production units with up-to-date technologies and comply with EU standards.
Antunovic, B., Bock, B.B., Kralik, G., Oosting, S.J., Wellbrock, W.   +4 more
core   +2 more sources

Molecular optimization, docking, and dynamic simulation profiling of selective aromatic phytochemical ligands in blocking the SARS-CoV-2 S protein attachment to ACE2 receptor: an in silico approach of targeted drug designing

Journal of Advanced Veterinary and Animal Research, 2021
Objectives: The comprehensive in silico study aims to figure out the most effective aromatic phytochemical ligands among a number from a library, considering their pharmacokinetic efficacies in blocking “angiotensin-converting enzyme 2 (ACE2) receptor ...
Dipta Dey, Parag Kumar Paul, Salauddin Al Azad, Mohammad Faysal Al Mazid, Arman Mahmud Khan, Md. Arman Sharif, Md. Hafijur Rahman   +6 more
semanticscholar   +1 more source

Analysis of Housing Risk Factors for the Welfare of Lean and Heavy Pigs in a Sample of European Fattening Farms

Animals, 2021
Pig welfare is affected by housing conditions, the minimum requirements of which are set up by EU legislation. Animal and non-animal-based measures are useful indicators to investigate housing risk factors for pig welfare.
Paolo Ferrari, Alessandro Ulrici, Matteo Barbari   +2 more
doaj   +1 more source

Based on network pharmacology and molecular docking to explore the protective effect of Epimedii Folium extract on cisplatin-induced intestinal injury in mice

Frontiers in Pharmacology, 2022
Background: Epimedii Folium, as a natural botanical medicine, has been reported to have protective effects on intestinal diseases by modulating multiple signaling pathways.
Juan Xia, Jun-Nan Hu, Zi Wang, E. Cai, Shen Ren, Ying-ping Wang, X. Lei, Wei Li   +7 more
semanticscholar   +1 more source

Design, synthesis and evaluation of novel 3,5-disubstituted benzamide derivatives as allosteric glucokinase activators

BMC Chemistry, 2019
Glucokinase (GK) is the key enzyme expressed in β-cells of pancreas and liver hepatocytes and helps in the maintenance of blood glucose levels in normal range.
Ajmer Singh Grewal, Rajeev Kharb, Deo Nandan Prasad, Jagdeep Singh Dua, Viney Lather   +4 more
doaj   +1 more source