Results 91 to 100 of about 1,751,019 (301)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Health and health promotion and applied health psychology in sexual and stigmatized minority populations : a collection of papers and a monograph presented in application for the degree of Doctor of Science at Massey University [PDF]
This Doctor of Science comprises a number of published works, listed in the attached file. As such due to copyright restriction they are not included here but can be accessed individually from the publisher.
Ross, Michael W.
core
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
New applications of algebraic curves [PDF]
筑波大学University of Tsukuba博士(経営工学)Doctor of Management Science and EngineeringOver the last two decades, several application of the algebraic curves over finite fields to information sciences have been developed: for example, algebraic-geometric codes ...
35101, Shinohara, Satoshi, 篠原, 聡
core
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Владимир Логвинович Рвачев – известный украинский ученый – математик-механик (к 85-летию со дня рождения) [PDF]
Статья посвящена памяти выдающегося ученого в отрасли математики, механики и кибернетики, заслуженного деятеля науки и техники Украины, лауреата Государственной премии Украины, в области науки и техники, обладателя орденов Ярослава Мудрого, Трудового ...
Курпа, Лидия Васильевна
core
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Профессор Арег Вагаршакович Дабагян – ученый и организатор высшей школы (к 90-летию со дня рождения) [PDF]
В статье представлен творческий путь известного украинского ученого, доктора технических наук, профессора А. В. Дабагяна. Посвящается 90-летию со дня рождения.In article the career of the known Ukrainian scientist – doctor of technical science professors
Ларин, Андрей Алексеевич
core

