Results 91 to 100 of about 1,751,019 (301)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Health and health promotion and applied health psychology in sexual and stigmatized minority populations : a collection of papers and a monograph presented in application for the degree of Doctor of Science at Massey University [PDF]

open access: yes, 2019
This Doctor of Science comprises a number of published works, listed in the attached file. As such due to copyright restriction they are not included here but can be accessed individually from the publisher.
Ross, Michael W.
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CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Analytics—doctors of sciences [PDF]

open access: yesJournal of Analytical Chemistry, 2009
openaire   +1 more source

New applications of algebraic curves [PDF]

open access: yes, 2000
筑波大学University of Tsukuba博士(経営工学)Doctor of Management Science and EngineeringOver the last two decades, several application of the algebraic curves over finite fields to information sciences have been developed: for example, algebraic-geometric codes ...
35101, Shinohara, Satoshi, 篠原, 聡
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Владимир Логвинович Рвачев – известный украинский ученый – математик-механик (к 85-летию со дня рождения) [PDF]

open access: yes, 2011
Статья посвящена памяти выдающегося ученого в отрасли математики, механики и кибернетики, заслуженного деятеля науки и техники Украины, лауреата Государственной премии Украины, в области науки и техники, обладателя орденов Ярослава Мудрого, Трудового ...
Курпа, Лидия Васильевна
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Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Профессор Арег Вагаршакович Дабагян – ученый и организатор высшей школы (к 90-летию со дня рождения) [PDF]

open access: yes, 2011
В статье представлен творческий путь известного украинского ученого, доктора технических наук, профессора А. В. Дабагяна. Посвящается 90-летию со дня рождения.In article the career of the known Ukrainian scientist – doctor of technical science professors
Ларин, Андрей Алексеевич
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