Results 91 to 100 of about 7,404,606 (267)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Notification law of Latvia

open access: yesУченые записки Казанского университета: Серия Гуманитарные науки, 2017
The paper deals with the legal aspects of notification problems of accomplished or planned official actions of courts, as well as administrative, civil, and legal enforcement systems and other institutions of power, administration, and control.
V.G. Sinitsyn
doaj  

Le documentaire critique et la représentation du travail ouvrier

open access: yesImages du Travail, Travail des Images, 2016
The photographic realism delivered to the public as to the researcher a fertile material to know and study the workers. The inclusion of photography in art created a new kind of realism, as photographers called the critical documentary.
Géraldine Millo
doaj   +1 more source

A workflow for document level interoperability [PDF]

open access: yes, 2011
This article describes a software environment called the Exchange Center that helps digital librarians manage the workflow of sourcing documents and metadata from various repositories.
Bainbridge, David, Cunningham, Sally Jo
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Typology of revolutions and Bibliologos

open access: yesБиблиосфера, 2021
The objectives of the research are as follows: 1. To substantiate the content of the transdisciplinary concept “Bibliologos” and to demonstrate its use in library and book science. 2.
A. V. Sokolov
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Visual analysis of document triage data [PDF]

open access: yes, 2011
As part of the information seeking process, a large amount of effort is invested in order to study and understand how information seekers search through documents such that they can assess their relevance. This search and assessment of document relevance,
Buchanan, George R.   +3 more
core   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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