Results 81 to 90 of about 7,404,606 (267)

Enfatizando o processo

open access: yesSignificação: Revista de Cultura Audiovisual, 2019
In response to the concept of an artistic project, technology has a double role: it hides the performer behind the computer and extends the possibilities by representing him/her.
Ana Carvalho
doaj  

Named Entity Recognition Using Web Document Corpus

open access: yes, 2011
This paper introduces a named entity recognition approach in textual corpus. This Named Entity (NE) can be a named: location, person, organization, date, time, etc., characterized by instances.
Karaa, Wahiba Ben Abdessalem
core   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Documents of the Society of Doctors at the Kazan University as a historical source (second half of the 1920s)

open access: yesУченые записки Казанского университета: Серия Гуманитарные науки, 2017
The paper describes the complex of documents that appeared as a result of the activities of the Society of Doctors at the Kazan University in the second half of the 1920s.
R.G. Ivanova, A.A. Salnikova
doaj  

Efficient Document Indexing Using Pivot Tree

open access: yes, 2016
We present a novel method for efficiently searching top-k neighbors for documents represented in high dimensional space of terms based on the cosine similarity. Mostly, documents are stored as bag-of-words tf-idf representation. One of the most used ways
Piwowarski, Benjamin, Singh, Gaurav
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

The functional semantic properties of motion verbs from the documents of Don Cossack Host province offices of the 18th – 19th centuries

open access: yesУченые записки Казанского университета: Серия Гуманитарные науки, 2017
The study has been performed as part of the collective research project no. 16-14-34004 supported by the Russian Foundation for Basic Research and the Government of the Volgograd region.
O.A. Gorban
doaj  

Home - About - Disclaimer - Privacy