Results 71 to 80 of about 612,651 (273)

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Compensatory Measures in European Nature conservation law [PDF]

, 2014
The Birds and Habitats Directives are the cornerstones of EU nature conservation law, aiming at the conservation of the Natura 2000 network, a network of protected sites under these directives, and the protection of species.
Van Hoorick, Geert
core   +3 more sources

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Butterflies (Lepidoptera) on Hill Prairies of Allamakee County, Iowa: A Comparison of the Late 1980s With 2013 [PDF]

, 2018
In the late 1980s, several hundred butterflies were collected by John Nehnevaj from hill prairies and a fen in Allamakee County, Iowa. Nehnevaj’s collection included 69 species, 14 of which are currently listed in Iowa as species of greatest conservation
Larsen, Kirk J, Powers, Nicole M
core   +2 more sources

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Progress in strain monitoring of tapestries

, 2008
This paper reports interdisciplinary research between conservators and engineers designed to enhance the long-term conservation of tapestries (tapestry-weave hangings) on longterm display.
Chambers, A.R., Dulieu-Barton, J.M., Eastop, D., Khennouf, D., Lennard, F., Ye, C.C.   +5 more
core  

Characterization of Kemp's Ridley Sea Turtles in the Florida Big Bend Area: Final report [PDF]

, 1998
The Kemp's ridley (Lepidochelys kempo is considered the most endangered of the seven extant marine turtle species (Ross et al. 1989). The US Fish and Wildlife Service (USFWS) and the National Marine Fisheries Service (NMFS) estimate the breeding ...
Barichivich, William J., Carthy, Raymond R., Sulak, Kenneth J.   +2 more
core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Conservation and concealment in SpeciesBanking.com, USA: an analysis of neoliberal performance in the species offsetting industry [PDF]

, 2011
Market-based strategies are promoted as neoliberal governance solutions to environmental problems, from local to global scales. Tradable mitigation schemes are proliferating.
Bayon, Bayon, Bonnie, Brockington, Carroll, Fleischer, Foucault, Harvey, Igoe, J. PAWLICZEK, Jackson, Mead, Ruhl, S. SULLIVAN   +13 more
core   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source