Results 111 to 120 of about 1,009,209 (280)

Documents/documentation

open access: yes, 2017
Documentation – that is, documents and practices with them (or documentary practices) – plays a central role in constituting and materializing information. Bernd Frohmann (2004) argues that information is an effect of documentation. He argues that attention to documents and documentary practices “reveals how it is that particular documents, at ...
openaire   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Cooperación Documental : el caso de México. [PDF]

open access: yes, 2002
El siguiente trabajo presenta los canales de cooperación que han desarrollado las instituciones documentales de México. Expone un panorama general en el que para ubicar las relaciones con mayor claridad, se incluyen los tipos de bibliotecas, las ...
Hernández Pacheco, Federico   +1 more
core   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

José Martí y la hegemonía estadounidense: Un análisis de su papel diplomático en la Conferencia Panamericana

open access: yesPolítica Internacional
El presente trabajo se propone realizar una aproximación a la labor periodística y diplomática realizada por José Martí, en el contexto de las conferencias panamericana y monetaria, celebradas en 1889 y 1891, respectivamente.
Ariel Alba Hernández
doaj  

Documental Primera base tricolor [PDF]

open access: yes, 2017
Primera Base Tricolor es un documental que pretende dar a conocer la importancia del arraigo del béisbol en la cultura caribe. Este deporte, a diferencia de otros deportes como el fútbol, se ha transmitido de generación en genaración.
Rincón Guzmán, Luisa María   +1 more
core  

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha   +4 more
wiley   +1 more source

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