Results 51 to 60 of about 32,540 (261)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Participatory Documentary Film as Interactive Documentary
+ ID der Publikation: hslu_107121 + Art des Beitrages: Präsentation Konferenzpapier/Tagungsbeitrag + Sprache: Englisch + Letzte Aktualisierung: 2025-03-21 11:27 ...
openaire +2 more sources
Le documentaire pour la jeunesse en Pologne avant et après 1989 : terminologie et critique
The goal of this article is to shed light on the place of documentaries within children’s book criticism in Poland from 1945 to present day. The article will start with the question of terminology and then proceed to past and current states of research ...
Agnieszka Wandel
doaj +1 more source
This article explains how, from 2012 to 2015, the authors conceived, shot and edited the film »Un Tribunal para la Constitución«, a documentary about the first years of the Constitutional Court of Spain.
Miguel Beltrán, Daniel Sarmiento
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Mapping research trends in shared decision-making for type 2 diabetes mellitus: a bibliometric study
BackgroundType 2 Diabetes Mellitus (T2DM) requires continuous and complex decision-making, including treatment initiation, therapy intensification, and lifestyle considerations.
Carla Salgado-Castillo +6 more
doaj +1 more source
Agnès Varda: filming the Black Panthers's Struggle
Agnès Varda directed two documentaries on the Black Panthers in 1968. Huey captures the militant atmosphere of the “free Huey” campaign whereas Black Panthers focuses on its local impact on the African American community of Oakland.
Delphine Letort
doaj +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source

