Results 61 to 70 of about 394,933 (283)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
La promotion du travail artistique par le cinéma : image de l’artiste et « travail de l’image »
Images du Travail, Travail des Images, 2016 Questionning the way film reflects upon artistic work compels us to consider the many ways in which “the observer is himself a part of the observation”, according to Lévi-Strauss famous comment of Marcel Mauss' sociological approach.
Jean-Marc Leveratto
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Black Virgins, Close Encounters : re-examining the ‘semi-documentary’ in postmigrant theatre [PDF]
, 2016 In 2006 the premiere of Feridun Zaimoglu and Günter Senkel’s play Black Virgins (Schwarze Jungfrauen) became the first play by a Turkish-German writer to feature on the front cover of Germany’s influential theatre magazine, Theater heute (Theatre Today).
Stewart, Lizzie
core +2 more sources
Les professionnels de l’image à l’écran : les cinéastes animaliers se mettent en scène
Images du Travail, Travail des Images, 2016 Filmmakers at work sometimes film themselves and offer spectators an exploration of what goes on behind the camera. These pictures of filmmakers work feature staging and editing which describe and accentuate specific characteristics (such as specific ...
Maxence Lamoureux
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Images du Travail, Travail des Images, 2018 This article is situated in the crossing of two current reflections : the one concerns the documentaries and the singularity of their point of view, compared with the social sciences ; other one aims at analyzing the possibility to film the contemporary ...
Jean-Paul Géhin
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source