Results 61 to 70 of about 207,894 (266)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

3D and 4D Simulations for Landscape Reconstruction and Damage Scenarios. GIS Pilot Applications [PDF]

, 2017
The project 3D and 4D Simulations for Landscape Reconstruction and Damage Scenarios: GIS Pilot Applications has been devised with the intention to deal with the demand for research, innovation and applicative methodology on the part of the ...
Pavia, Davide, Pesaresi, Cristiano, VAN DER SCHEE, Joop   +2 more
core   +2 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Walking the talk : an investigation of the pedagogical practices and discourses of an international broadcasting organisation : a thesis presented in partial fulfilment of the requirements for the degree of Master of Education in Adult Education, Massey University, Manawatu, New Zealand [PDF]

, 2011
Increasingly our knowledge of the world around us comes from the media, mediated by professional broadcasters. As the education and training of broadcasters has progressively become associated with educational institutions there has been more ...
Quade, Victoria Nancy Tippett, Quade, Victoria Nancy Tippett   +1 more
core  

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

"A step into the abyss" Transmedia in the UK Games and Television Industries [PDF]

, 2016
This article uses a media industries studies perspective to investigate the current state of transmedia production in the UK. Analysing the discursive statements of a range of industry participants from both UK television and games industries, the ...
Johnston, Keith M, Phillips, Tom
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

¿Es posible una gestión humana no funcionalista? Descripción de un modelo estratégico de gestión de personal

Universidad y Empresa, 2010
This paper describes a human management model as conceived in organizations that carry out a strategic direction of staff, based on a critical look of traditional management and some of its notions, such as the classical perspective of strategic ...
Héctor Bermúdez Restrepo
doaj  

Evaluation of the administrative management model in a municipality in Peru, incorporating the Intelligent Organization Theory [version 1; peer review: 2 approved]

F1000Research
Background This study begins with the analysis of the current management models and their degree of effectiveness in municipal administration. Its aim is to design an administrative management model that enables effective administration in the District ...
Carlos Hugo Luna Rioja, José Carloman Saldaña Castillo, José Elider Tarrillo Carrasco, José Humberto Becerra Santa Cruz, Nikolays Pedro Lizana Guevara, Cynthia Vanessa Coronel Benites, Rogger Orlando Morán Santamaría, Francisco Eduardo Cúneo Fernández   +7 more
doaj   +1 more source

Nominee handbook for schools and PRUs, from September 2010 [PDF]

, 2010
"This handbook is designed for nominees who will be the school representative on the inspection team during their school's inspection. The handbook has primarily been developed with the needs of school headteachers, deputy headteachers and senior ...

core