Results 111 to 120 of about 2,502,152 (334)

Model documentation, chapter 4 [PDF]

open access: yes
The modeling groups are listed along with a brief description of the respective ...
Crisp, David   +9 more
core   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

“Avanguardie Educative”: paths of innovation for schools

open access: yesResearch on Education and Media, 2016
This article presents “Avanguardie Educative” (http://avanguardieeducative.indire.it/), a cultural movement founded to gather the most significant experiences of organizational and educational innovation in Italian schools and encourage transformation of
Laici Chiara, Orlandini Lorenza
doaj   +1 more source

Notes Documentaires et Études, n° 918 (série française. - CXCII). La lecture publique en France [PDF]

open access: yes
« Document numérisé pour l\u27ENSSIB » - Réalisé par la Direction de la documentation, ce document officiel s\u27adresse aux professionnels. Dans le cadre de ce corpus, il s\u27inscrit dans un ensemble de trois brochures de "Notes et Études Documentaires"
Direction de la Documentation
core   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

open access: yesMolecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh   +5 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Lexical–Syntactic Classes of Adjectives in Copular Sentences across Spanish Varieties: The Innovative Use of Estar

open access: yesLanguages
This paper aims to provide a clearer understanding of the structure known in the literature as the innovative use of estar, illustrated in sentences like Luego salgo/voy a visitar usuarios que están muy morosos [Medellín, Colombia; Preseea] (“Today I am ...
Silvia Gumiel-Molina   +2 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

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