Results 81 to 90 of about 2,560,284 (292)

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Persistence and Evolution Within Interactive Design: An Integrated Approach to ICT Innovations in Emergent Game Narratives

open access: yesTechnologies
Video games, as interactive artifacts within the continuum of information and communication technology (ICT), encapsulate an ontological inquiry: which mechanism maintains user engagement while evolving with ICT-driven innovations?
Mengfan Zou   +3 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

A Study of Methods to Identify Industry-University-Research Institution Cooperation Partners based on Innovation Chain Theory

open access: yesJournal of Data and Information Science, 2018
This study aims at identifying potential industry-university-research collaboration (IURC) partners effectively and analyzes the conditions and dynamics in the IURC process based on innovation chain theory.
Xu Haiyun   +5 more
doaj   +1 more source

Integrating Experimental Methods, Language Documentation, and (Linguistic) Theory [PDF]

open access: yes, 2016
Syllabus for workshop presented at CoLang 2016.Language documentation and linguistic theories mutually benefit from cooperation - data from documentation propels linguistic theories, and different theories can inform the collection of language materials.
Lee, Seunghun, Temkin Martínez, Michal
core  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

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