Results 81 to 90 of about 597,454 (292)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

FID news bulletin.

open access: yes, 1951
Mode of access: Internet.Contains administrative material and news formerly published in Revue de la ...
International Federation for Documentation.
core  

End-user documentation [PDF]

open access: yes, 2003
The first and most basic problem with documentation is that the consumer of software applications does not want to use the documentation included with a software product for one or more reasons.
Wilkinson, Paul Johnston
core  

Identification of R&D Teams Based on the Disambiguationof Patent Inventors’ Names

open access: yesZhishi guanli luntan, 2016
[Purpose/significance] Talent is the main factor in technology research. R&D teamsare the focus of technology development in various fieldsandimportant manifestation of the competence of an institution.
ZhangJing, Zhang Zhiqiang, Zhao Yajuan
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Information Science : Information as a Dialectic Interactive System [PDF]

open access: yes, 1995
Mankind is passing through historical moments of great change and transformation. The human being, from the centre of his own world, is trying to get to know and analyse the surrounding macrocosmos and microcosmos, also part of his environment, in order ...
Currás, Emilia
core   +1 more source

Documentation, Information and the Animal Connection

open access: yesProceedings from the Document Academy, 2016
The article elaborates on the informational relationship between nature, animals and humans. In traditional societies, nature and animals are rich sources of information and documentation, as seen in Sámi reindeer husbandry.
Geir Grenersen
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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