Results 91 to 100 of about 597,454 (292)
Joint PADIS / SADIS Consultative Meeting of Information and Documentation Scientists, Policy Makers, Researchers and Experts on Technical Cooperation from Southern African Governments, Salisbury, Zimbabwe, 22-26 Feb. 1982 [PDF]
Meeting: Joint PADIS / SADIS Consultative Meeting of Information and Documentation Scientists, Policy Makers, Researchers and Experts on Technical Cooperation from Southern African Governments, 22-26 Feb.
Pan-African Documentation and Information System +1 more
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
The need for information literacy skills among users of European Union information [PDF]
The aim of this paper is the assessment of information literacy skills related to European topics, among a group of 234 users of 55 European Documentation Centres (EDCs), from 21 European Union Member- States.
Terra, Ana Lúcia
core +1 more source
Aims Cancer is one of the main causes of death in persons with severe mental illness (SMI). Although their cancer incidence is similar, or sometimes even potentially lower compared to the general population, their cancer mortality remains higher.
A.-V. Seppänen +5 more
doaj +1 more source
Information Literacy Skills of Management Sciences’ Students
The objective of this study was to determine the information literacy (IL) skills of Management Sciences students. A questionnaire was adopted to collect data from 254 currently enrolled graduate and undergraduate students of two universities, one public
Ghulam Murtaza Rafique, Hina Asif Khan
doaj +1 more source
The establishment and maintenance of relevant documentation and reports are necessary to facilitate an effective and efficient operation.
openaire +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source

