Results 111 to 120 of about 612,079 (291)
ANTROPONYMS AS AN OBJECT OF LINGUO-CRIMINALISTIC EXPERTIZE
Неофилология, 2016 The notion linguistic expertise is understood. Linguistic research is often hidden in this notion. It is proved that it is the example of onomastic research diversification. It is established that Russian citizens have difficult problems with equal legal
Mikhail Viktorovich Gorbanevskiy +1 more
doaj
, 1981 Meeting: Information and Documentation : the Expectations of Developing Countries, 16-17 Nov. 1981, Montreal, Que., CAMeeting: Association pour l'avancement des sciences et des techniques de la documentation, Colloque, 2e, 16-17 nov. 1981, Montréal,
Monge, F.
core
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
FEBS Letters, EarlyView.The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source
Recensione III World Patent Information
, 2015 Recensione III World Patent Information: The International Journal for Industrial Property Documentation, Information, Classification and ...
THOMA, Grid
core +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
International information systems (DEVSIS)
, 1983 Meeting: European Cooperation in Development Information and Documentation, 9-14 Oct.
De Mautort, R.T.
core +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source