Results 41 to 50 of about 2,420 (113)
Clinical and Translational Medicine, Volume 14, Issue 8, August 2024.Pgam5 knockout attenuates alcohol‐induced cardiac histopathology and heart dysfunction in male mice. Pgam5 interacts with Phb2 and induces Phb2 dephosphorylation. Disruption of Pgam5/Phb2 binding reduces EtOH‐induced mitochondrial quality control impairment in cardiomyocytes. Mice genetically modified to express a phosphor‐mimetic Phb2 mutant at serine
Jun Tao +5 more
wiley +1 more source
Advanced Healthcare Materials, Volume 13, Issue 17, July 5, 2024.This review summarizes key issues and offers suggestions for the novel use and integration of smart biosensors in real‐time health monitoring process, as well as provides insight into their material functionality and technological approaches. With smart established systems, bioelectronics can be able to accurately provide capabilities for diagnosing ...
Thi Sinh Vo +5 more
wiley +1 more source
Preparation of Neurospora crassa mitochondria [PDF]
, 1978 The fungus Neurospora crassa represents a eukaryotic cell with high biosynthetic activities. Cell mass doubles in 2-4 hr during expone ntial growth , even in simple salt media with sucrose as the sole carbon source. The microorgani sm forms a mycelium of
Jacki +11 more
core +2 more sources
Advanced Therapeutics, Volume 7, Issue 2, February 2024.Encapsulins are prokaryotic protein nanocages that show promise as nanoparticle‐based drug delivery systems. However, the in vivo behavior of encapsulins is poorly understood. This study elucidates the formulability, nanosafety, immunogenicity, protein corona, biodistribution, and clearance of intravenously injected nanocages.
Claire Rennie +7 more
wiley +1 more source
Cardioprotective and antioxidant effects of Bougainvillea glabra against isoproterenol induced myocardial necrosis in albino rats [PDF]
, 2018 The present study was executed to evaluate the myocardial protective effect of methanol extract of Bougainvillea glabra against isoproterenol induced myocardial necrosis in rats. Myocardial necrosis was induced by subcutaneous injection of isoproterenol (
Raja Sundara Rajan, Rakam Gopi Krishna
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Methods of endotoxin removal from biological preparations : a review [PDF]
, 2007 PURPOSE: Endotoxins, also called lipopolysaccharides (LPS), are major contaminants found in commercially available proteins or biologically active substances, which often complicate study of the biological effects of the main ingredient.
Batista, Pérola de Oliveira Magalhães Dias +5 more
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The ubiquitin-proteasome system in neurodegeneration [PDF]
, 2014 SIGNIFICANCE: Impairment of the ubiquitin-proteasome system (UPS) has been implicated in the pathogenesis of a wide variety of neurodegenerative disorders, including Alzheimer's, Parkinson's, and Huntington's diseases.
McKinnon, C, Tabrizi, SJ
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Electrochemical Biosensors Based on Enzyme Inhibition Effect
The Chemical Record, Volume 24, Issue 2, February 2024.Several electrochemical biosensors based on various enzyme inhibition effects have been designed; their laboratory prototypes have been manufactured and thoroughly investigated. It should be noted that such biosensors are adapted to large‐scale production technologies.
Valentyna Arkhypova +3 more
wiley +1 more source
Journal of Cellular and Molecular Medicine, Volume 28, Issue 3, February 2024.Abstract Ferroptosis, characterized by lipid accumulation in intracellular compartments, is related to acute kidney injury (AKI), but the mechanism remains obscure. In our previous study, the protective effect of augmenter of liver regeneration (ALR) on AKI was not fully clarified.
Lili Huang +11 more
wiley +1 more source
Purification and characterisation of 20S proteasome from ostrich skeletal muscle and its role in meat tenderisation [PDF]
, 2004 The proteasome is renowned for its high molecular weight, multisubunit and mulicatalytic nature. One of its many suggested roles is the degradation of myofibrillar proteins, and therefore it has been proposed to play a role in the meat tenderisation ...
Thomas, Adele René
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