Results 41 to 50 of about 3,849,410 (219)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Miniaturized wireless bioelectronics for electrically driven biohybrid robots

open access: yesScientific Reports
Although biohybrid robots offer the potential for soft, adaptive actuation by harnessing living muscle, practical operation in cell culture environments is often limited by the requirement of immersed leads or cumbersome stimulation equipment.
Hiroyuki Tetsuka   +2 more
doaj   +1 more source

Acoustic Characteristics of Spawning Biological Sounds of Brown Croaker (Miichthys miiuy)

open access: yesFishes
Marine organisms make sounds for various reasons, including spawning and avoidance, which are species-specific. Traditionally, Korean fishermen in the northwest Pacific Ocean have listened for spawning sounds to locate spawning grounds of Brown croaker ...
Hansoo Kim   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Performance‐Conscious Coadditive Approach for Enhancing Proton Exchange Membrane Durability: Roles of Tungsten Oxides and Cerium Ions

open access: yesChemElectroChem
To improve the chemical durability of proton exchange membrane fuel cells (PEMFCs) while imposing minimal performance penalties, the effects of simultaneously incorporating tungsten oxide (WOx) and cerium (Ce) ions into the membrane are evaluated.
Kazuma Shinozaki   +8 more
doaj   +1 more source

Unstable simultaneous whirl of two cylinders in a concentric double rotating cylinder system

open access: yesMechanical Engineering Journal
This study investigated the unstable simultaneous whirl of two cylinders in a concentric double rotating cylinder system, with both co- and counter-rotation. The axes of both cylinders were radially elastically supported independently of each other.
Fumitaka YOSHIZUMI, Masanori IRITANI
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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