Results 51 to 60 of about 3,849,410 (219)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Literary Domains’ Connectionin a Policultural Text
RUDN Journal of Language Studies, Semiotics and Semantics, 2019 The authors of the article consider semiotic systems of different levels of organization as databases - domains that accumulate the number of relay units over time and communicate with each other, generating new containers of cultural information.
Vladimir Pavlovich Sinyachkin +2 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
O conceito de bioma The biome concept
Acta Botânica Brasílica, 2006 O termo fitofisionomia foi proposto praticamente ao mesmo tempo que o termo formação. O termo bioma, proposto mais tarde, apenas adicionou a fauna à uniformidade fitofisionômica e climática, características desta unidade biológica.
Leopoldo Magno Coutinho
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Journal of Power Sources AdvancesAs polymer electrolyte fuel cells (PEFCs) become more widespread, there is growing demand to reduce the environmental impact of their production and to comply with regulations covering perfluoroalkyl and polyfluoroalkyl substances (PFAS).
Tetsushi Ohmura +4 more
doaj +1 more source
ASPECTS OF THE ROMANIAN INDUSTRY DEVELOPMENT [PDF]
Economica, 2018 In this article, the authors sought to analyse a longer period, since 1948 (when the process of nationalization of industry, banking, insurance, mining and transportation) took place until today.
Constantin ANGHELACHE +2 more
doaj
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Geo-spatial Information ScienceAccurately estimating ambient population density, which refers to the number of people present in a location at a specific time, is critical for effective urban planning, disaster response, and infrastructure management.
Yoshinao Ishii +2 more
doaj +1 more source