Results 71 to 80 of about 3,849,410 (219)

METAPHOR SCENARIOS IN PSYCHOTERAPEUTIC DISCOURSE BY IRVIN YALOM

Іноземна філологія
The article focuses on investigating psychotherapeutic discourse in view of cognitive linguistic approach. The objective of the present research is to reveal and describe the metaphor scenarios that constitute the range of the conceptual metaphor with ...
Oksana Doichyk, Iryna Shkoruta
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

“Purpose” and “Domain”: Two Concepts Translated as “Sonzai-igi,” and Their Relationship to “Keiei-rinen”

AAOS Transactions
The terms “purpose” and “domain” are both translated as “Sonzai-igi.” Furthermore, “purpose” is also said to be included within “Keiei-rinen.” Based on previous research, this study documents the relationship between “Keiei-rinen,” “purpose,” and “domain,
Haruhiko NOBAYASHI
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

A VIKOR-Based Sequential Three-Way Classification Ranking Method

Algorithms
VIKOR uses the idea of overall utility maximization and individual regret minimization to afford a compromise result for multi-attribute decision-making problems with conflicting attributes.
Wentao Xu, Jin Qian, Yueyang Wu, Shaowei Yan, Yongting Ni, Guangjin Yang   +5 more
doaj   +1 more source

Endorsement of parental authority in adolescence: Bedouin vs. Jewish adolescents in Israel

International Journal of Adolescence and Youth, 2018
The study examines Bedouin and Jewish adolescents’ endorsement of parental authority, in an attempt to clarify the role of culture in the context of parent–child authority relations in the family.
Yosi Yaffe, Dominique-Esther Seroussi, Sale Kharanbeh   +2 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

The role of SPINK5 mutation distribution in phenotypes of Netherton syndrome

Frontiers in Genetics
ObjectiveNetherton syndrome (NS) is a rare hereditary dermatosis, and the correlation between genotype and phenotype in this disease warrants further investigation.
Min Xu, Yujie Shi, Li Lin, Liang Wang, Xianzhong Zhu, Jinglin Xiong, Jiawen Yin, Qing Qi, Wenlin Yang   +8 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source