Results 51 to 60 of about 1,143 (217)

The Approximate Solution of 2D Dirichlet Problem in Doubly Connected Domains

Advances in Mathematical Physics, 2018
We propose a new method for constructing an approximate solution of the two-dimensional Laplace equation in an arbitrary doubly connected domain with smooth boundaries for Dirichlet boundary conditions.
Atallah El-shenawy, Elena A. Shirokova
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

The Control Problem for a Heat Conduction Equation with Neumann Boundary Condition

Vestnik KRAUNC: Fiziko-Matematičeskie Nauki
Previously, boundary control problems for a heat conduction equation with Dirichlet boundary condition were studied in a bounded domain. In this paper, we consider the boundary control problem for the heat conduction equation with Neumann boundary ...
Dekhkonov, F.N.
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

A time-domain integration method with equivalent complex damping model based on viscoelastic material constitutive relation

Journal of Low Frequency Noise, Vibration and Active Control
The complex damping model is only applied in frequency-domain. Based on the constitutive relation of viscoelastic materials, a vibration equation is equivalent to the constitutive relation of complex damping theory and the frequency response function ...
Jia Fan, Shuxia Wang, Panxu Sun
doaj   +1 more source

Electromagnetic Field Analysis of Operation Space of the Switch in the Substation Based on the Time Domain Integration Method

E3S Web of Conferences, 2018
In this paper, the approximate calculation formula is used to calculate the horizontal electric field from lightning which has arbitrary current, with the help of time domain integral equation method solving the lightning induced over voltages on ...
ZHANG Jian-gong, Zhao Jun, GAN zheyuan, ZHANG yemao, LU ying   +4 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

STRUCTURAL GLOBAL SENSITIVITY METHOD BASED ON PARTIAL DERIVATIVE WHOLE DOMAIN INTEGRAL

Jixie qiangdu, 2019
In view of the problems that the traditional variance-based Sobol’method had a low solving efficiency,lacked of enough robustness,and it cannot further effectively decompose and reasonably distribute the influences of the high-order cross subterms,a ...
TU LongWei, LIU Jie, LIU GuangZhao, ZHANG Zheng   +3 more
doaj