Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
PSRNet: a phase-guided frequency-domain structure reconstruction network for RGB-T salient object detection. [PDF]
Front NeurorobotXie F, Zhou J, Gao F, Ma X, Yang C.
europepmc +1 more source
The Distinctive Permutated Domain Structure of Periplasmic α-Amylase (MalS) from Glycoside Hydrolase Family 13 Subfamily 19. [PDF]
Molecules, 2023 An Y +7 more
europepmc +1 more source
Molecular Oncology, EarlyView.Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler +3 more
wiley +1 more source
Domain Structure Transformation and Impedance Tuning in Partially Nanocrystallized Fe-Based Microwires. [PDF]
Sensors (Basel)Aksenov O, Fuks A, Aronin A.
europepmc +1 more source
High-Strength Heat-Elongated Thermoplastic Polyurethane Elastomer Consisting of a Stacked Domain Structure. [PDF]
Polymers (Basel), 2022 Takano M, Takamatsu K, Saito H.
europepmc +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
GluD1 at the synaptic crossroads: from domain structure to circuit dysfunction. [PDF]
Acta Pharmacol SinChettiar PB, Dravid SM.
europepmc +1 more source
Correction to: Distinct functions of FASCICLIN-LIKE ARABINOGALACTAN PROTEINS relate to domain structure. [PDF]
Plant Physiol, 2023 europepmc +1 more source
Tandem domain structure determination based on a systematic enumeration of conformations. [PDF]
Sci Rep, 2021 Malliavin TE.
europepmc +1 more source