Results 71 to 80 of about 83,143 (263)

Mycobacterium tuberculosis CarD, an essential global transcriptional regulator forms amyloid-like fibrils

open access: yesScientific Reports, 2018
CarD is an essential global transcription regulator from Mycobacterium tuberculosis (Mtb) that binds RNA polymerase and activates transcription by stabilizing the transcription initiation complex.
Gundeep Kaur   +5 more
doaj   +1 more source

Energetic differences between non-domain-swapped and domain-swapped chain connectivities in the K2P potassium channel TRAAK

open access: yesRSC Advances, 2018
In the available crystallographic structures of K2P channels, the cap is present as non-domain-swapped (NDS) and domain-swapped (DS) chain conformations.
Carlos Navarro-Retamal, Julio Caballero
openaire   +3 more sources

Optoelectronic Synaptic Devices Using Molecular Telluride Phase‐Change Inks for Three‐Factor Learning

open access: yesAdvanced Functional Materials, EarlyView.
Optoelectronic synaptic devices based on solution‐processed molecular telluride GST‐225 phase‐change inks are demonstrated for three‐factor learning. A global optical signal broadcast through a silicon waveguide induces non‐volatile conductance updates exclusively in locally electrically flagged memristors.
Kevin Portner   +14 more
wiley   +1 more source

Biological Activities of Secretory RNases: Focus on Their Oligomerization to Design Antitumor Drugs

open access: yesFrontiers in Immunology, 2019
Ribonucleases (RNases) are a large number of enzymes gathered into different bacterial or eukaryotic superfamilies. Bovine pancreatic RNase A, bovine seminal BS-RNase, human pancreatic RNase 1, angiogenin (RNase 5), and amphibian onconase belong to the ...
Giovanni Gotte, Marta Menegazzi
doaj   +1 more source

The 25 kDa HCN Domain of Clostridial Neurotoxins Is Indispensable for Their Neurotoxicity

open access: yesToxins, 2020
The extraordinarily potent clostridial neurotoxins (CNTs) comprise tetanus neurotoxin (TeNT) and the seven established botulinum neurotoxin serotypes (BoNT/A-G).
Julian Deppe   +3 more
doaj   +1 more source

Towards Instance-level Image-to-Image Translation

open access: yes, 2019
Unpaired Image-to-image Translation is a new rising and challenging vision problem that aims to learn a mapping between unaligned image pairs in diverse domains.
Huang, Mingyang   +4 more
core   +1 more source

A domain swap makes motor rings [PDF]

open access: yesScience, 2016
Structural Biology Cells are packed with protein complexes. Cells must appropriately assemble these complexes while ensuring that component proteins do not aggregate prematurely. Baker et al. show that the FliG protein, part of the bacterial flagellar motor complex, can polymerize to forms rings by “domain swapping.” Domains within a single FliG can ...
openaire   +1 more source

Generative Models for Crystalline Materials

open access: yesAdvanced Materials, EarlyView.
Generative machine learning models are increasingly used in crystalline materials design. This review outlines major generative approaches and assesses their strengths and limitations. It also examines how generative models can be adapted to practical applications, discusses key experimental considerations for evaluating generated structures, and ...
Houssam Metni   +15 more
wiley   +1 more source

CirPred, the first structure modeling and linker design system for circularly permuted proteins

open access: yesBMC Bioinformatics, 2021
Background This work aims to help develop new protein engineering techniques based on a structural rearrangement phenomenon called circular permutation (CP), equivalent to connecting the native termini of a protein followed by creating new termini at ...
Teng-Ruei Chen   +4 more
doaj   +1 more source

Magnetic shape-memory effects in La2-xSrxCuO4 crystals

open access: yes, 2002
The magnetic field affects the motion of electrons and the orientation of spins in solids, but it is believed to have little impact on the crystal structure.
A. N. Lavrov   +6 more
core   +1 more source

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