Results 81 to 90 of about 83,637 (272)

Towards Instance-level Image-to-Image Translation

, 2019
Unpaired Image-to-image Translation is a new rising and challenging vision problem that aims to learn a mapping between unaligned image pairs in diverse domains.
Huang, Mingyang, Huang, Thomas, Shen, Zhiqiang, Shi, Jianping, Xue, Xiangyang   +4 more
core   +1 more source

Energetic differences between non-domain-swapped and domain-swapped chain connectivities in the K2P potassium channel TRAAK

RSC Advances, 2018
In the available crystallographic structures of K2P channels, the cap is present as non-domain-swapped (NDS) and domain-swapped (DS) chain conformations.
Carlos Navarro-Retamal, Julio Caballero
openaire   +3 more sources

Curvature‐Tuned Friction at Electrified Ionic Liquid Interfaces

Advanced Functional Materials, EarlyView.
Graphene curvature plays a key role in friction electrotunability at single‐asperity contacts lubricated by ionic liquids. A 9 nm radius yields stronger tunability than larger radii, with distinct friction coefficients at low and high loads indicating a shift in the slippage plane.
Wei Song, Md Ashiqur Rahman, Qianlu Zheng, Nathaniel Hawthorne, James D. Batteas, Rui Qiao, Rosa M. Espinosa‐Marzal   +6 more
wiley   +1 more source

The 25 kDa H_CN Domain of Clostridial Neurotoxins Is Indispensable for Their Neurotoxicity

Toxins, 2020
The extraordinarily potent clostridial neurotoxins (CNTs) comprise tetanus neurotoxin (TeNT) and the seven established botulinum neurotoxin serotypes (BoNT/A-G).
Julian Deppe, Jasmin Weisemann, Stefan Mahrhold, Andreas Rummel   +3 more
doaj   +1 more source

A domain swap makes motor rings [PDF]

Science, 2016
Structural Biology Cells are packed with protein complexes. Cells must appropriately assemble these complexes while ensuring that component proteins do not aggregate prematurely. Baker et al. show that the FliG protein, part of the bacterial flagellar motor complex, can polymerize to forms rings by “domain swapping.” Domains within a single FliG can ...
openaire   +1 more source

Mapping Nanoscale Protein‐Corona Kinetics of DoE‐Optimized Perfluorocarbon Encapsulated‐PLGA Nanoparticles by In Situ, Time‐Resolved Synchrotron SAXS

Advanced Healthcare Materials, EarlyView.
A two‐phase workflow (OFAT screening followed by central composite design) maps how processing variables tune PFCE‐PLGA nanoparticle size, dispersity, surface charge, loading, and 19F‐MRI signal. In situ, time‐resolved synchrotron SAXS tracks albumin‐corona growth on intact dispersions and reveals PFCE‐dependent adsorption pathways.
Joice Maria Joseph, Maria Rosa Gigliobianco, Cristina Minnelli, Paolo Moretti, Francesco Spinozzi, Giovanna Mobbili, Sara Pistolesi, Cristina Casadidio, Gabriella Teti, Roberta Censi, Stefano Antonio Gattone, Piera Di Martino   +11 more
wiley   +1 more source

CirPred, the first structure modeling and linker design system for circularly permuted proteins

BMC Bioinformatics, 2021
Background This work aims to help develop new protein engineering techniques based on a structural rearrangement phenomenon called circular permutation (CP), equivalent to connecting the native termini of a protein followed by creating new termini at ...
Teng-Ruei Chen, Yen-Cheng Lin, Yu-Wei Huang, Chih-Chieh Chen, Wei-Cheng Lo   +4 more
doaj   +1 more source

Consensus Formation and Change are Enhanced by Neutrality

Advanced Science, EarlyView.
Neutral agents are shown to enhance both the formation and overturning of consensus in collective decision‐making. A general mathematical model and experiments with locusts and humans reveal that neutrality enables robust consensus via simple interactions and accelerates consensus change by reducing effective population size.
Andrei Sontag, Janina A. Hoffmann, Tim Rogers, Christian A. Yates   +3 more
wiley   +1 more source

Conformable Microelectrode Arrays Integrated with a Scoop‐Shaped Slide‐Well for Dynamic Electrophysiological Profiling of Patient‐Derived Cardiac Organoids

Advanced Science, EarlyView.
A flexible, ultrathin multi‐channel microelectrode array (MEA) conformally integrated onto a curved slide‐well enables stable electrical interfacing with 3D cardiac organoids. The geometry‐guided self‐alignment allows simultaneous recording of extracellular field potentials and contractile motion from irregular, beating tissues.
Ye Seul Kim, Jeonghwa Jeong, Gyeonghwa Heo, Young Woo Kwon, Jeongha Lee, Yoon Ji Jeong, Gyu Tae Park, Seongdo Jeong, Ki Won Hwang, Murim Choi, Jinhong Shin, Suck Won Hong, Jae Ho Kim   +12 more
wiley   +1 more source

Double domain swapping in bovine seminal RNase: formation of distinct N- and C-swapped tetramers and multimers with increasing biological activities.

PLoS ONE, 2012
Bovine seminal (BS) RNase, the unique natively dimeric member of the RNase super-family, represents a special case not only for its additional biological actions but also for the singular features of 3D domain swapping.
Giovanni Gotte, Alexander Mahmoud Helmy, Carmine Ercole, Roberta Spadaccini, Douglas V Laurents, Massimo Donadelli, Delia Picone   +6 more
doaj   +1 more source