Results 91 to 100 of about 22,091 (247)
Type 1 secretion necessitates a tight interplay between all domains of the ABC transporter
Scientific ReportsType I secretion systems (T1SS) facilitate the secretion of substrates in one step across both membranes of Gram-negative bacteria. A prime example is the hemolysin T1SS which secretes the toxin HlyA.
Manuel T. Anlauf +6 more
doaj +1 more source
The N Terminus of the OB Domain of Telomere Protein TPP1 Is Critical for Telomerase Action
Cell Reports, 2018 Summary: Telomerase recruitment to telomeres and enzymatic processivity are mediated by TPP1, an essential component of telomere integrity and telomerase function.
Sherilyn Grill +2 more
doaj +1 more source
Hierarchical Physical‐Cyber Encryption via Metasurface‐Encoded Holographic Keys
Advanced Science, EarlyView.ABSTRACT Physical‐layer encryption based on metasurfaces has emerged as a promising alternative to conventional algorithmic cryptography by embedding security into physical processes. However, most existing metasurface‐based encryption schemes operate within single‐stage or static frameworks, where correct physical illumination directly reveals the ...
Zhen Liu +8 more
wiley +1 more source
Journal of Lipid Research, 2015 The ω6 and ω3 pathways are two major pathways in the biosynthesis of PUFAs. In both of these, delta 6 desaturase (FADS6) is a key bifunctional enzyme desaturating linoleic acid or α-linolenic acid.
Haisu Shi (史海粟) +6 more
doaj +1 more source
A domain swap makes motor rings [PDF]
Science, 2016 Structural Biology Cells are packed with protein complexes. Cells must appropriately assemble these complexes while ensuring that component proteins do not aggregate prematurely. Baker et al. show that the FliG protein, part of the bacterial flagellar motor complex, can polymerize to forms rings by “domain swapping.” Domains within a single FliG can ...
openaire +1 more source
Leading the Pack: Next‐Generation Batteries for Humanoid Robotics
Advanced Science, EarlyView.Humanoid robots challenge traditional and anticipated energy technologies. Humanoid robot benchmarks of runtimes and energy demands for industry applications inform humanoid robot battery design choices at the cell level, pack level, and system level.
Matthew Bergschneider +6 more
wiley +1 more source
Advanced Science, EarlyView.Computational and structure‐guided arginine scanning rewires the DNA‐binding interface of APE1 to create APE1‐Evo, a hyperactive yet specific AP endonuclease. Integrated into the NAPTUNE‐V2.0 cascade, APE1‐Evo enables amplification‐free, multiplex viral RNA sensing for dengue virus and influenza A/B, highlighting a general strategy for engineering ...
Junlan Wang +20 more
wiley +1 more source
N–O Dual Functional Group Transposition via Energy Transfer Photocatalysis
Advanced Science, EarlyView.N–O dual functional group transposition (dFGT) enabled by the photocatalytic energy transfer (EnT) has been developed. This methodology is applicable to both activated and unactivated alkyl derivatives for dFGT, and it also successfully extended to N–N dFGT, demonstrating its general applicability.
Lei Bao +4 more
wiley +1 more source
Structural and thermodynamic insights into antibody light chain tetramer formation through 3D domain swapping. [PDF]
Nat Commun, 2023 Sakai T +10 more
europepmc +1 more source
Advanced Science, EarlyView.This work demonstrates a design paradigm of phonon‐driven negative‐thermal‐expansion (NTE) flexible framework that exploits the intrinsic lattice flexibility of NTE frameworks to simultaneously suppress thermal expansion and activate oxide‐ion conduction, offering a promising strategy to mitigate TEC mismatch in solid‐state ionic devices.
Xiaohui Li +10 more
wiley +1 more source