Results 91 to 100 of about 1,858,101 (277)

MAGUK SH3 Domains—Swapped and Stranded by Their Kinases? [PDF]

open access: yesStructure, 2002
Excitement in protein science comes from unexpected structural findings that shed new light on functional mechanisms. Just such a series of insights is now beginning to emerge from two recently published structures of the scaffolding protein PSD-95.
openaire   +2 more sources

SPADE: A Deep Learning Framework for Spatial Mapping and Quantitative Cell–Cell Interaction Inference

open access: yesAdvanced Science, EarlyView.
SPADE integrates spatial transcriptomics with single‐cell RNA sequencing by using cell–cell communications (CCC) as a guide for spatial mapping. It improves cell‐type localization, enhances sparse gene‐expression signals, and reveals CCC programs at single‐spot resolution.
Xinyi Li, Ning Zhang, Zijie Jin
wiley   +1 more source

Tandem Duplication‐Driven Neofunctionalization of UDP‐Glycosyltransferases Shapes the Diversification of Triterpenoid Saponins in the Cucurbitaceae

open access: yesAdvanced Science, EarlyView.
We present a chromosome‐level genome assembly of Siraitia grosvenorii and, through comparative genomics, uncover a conserved UGT73 tandem array driving triterpenoid saponin diversification in Cucurbitaceae. Crystalized SgUGT73AM30 further reveals the regioselectivity mechanism underlying its catalytic activity.
Guangyi Wang   +13 more
wiley   +1 more source

The β‐domain of streptokinase affects several functionalities, including specific/proteolytic activity kinetics

open access: yesFEBS Open Bio, 2019
Streptokinase (SK) is a plasminogen activator which converts inactive plasminogen (Pg) to active plasmin (Pm), which cleaves fibrin clots. SK secreted by groups A, C, and G Streptococcus (SKA/SKC/SKG) is composed of three domains: SKα, SKβ and SKγ ...
Maryam Rafipour   +4 more
doaj   +1 more source

Enhanced Ionic Conductivity at the Solid Electrolyte Interphase of Oxygen‐Doped Li6PS5Cl

open access: yesAdvanced Science, EarlyView.
Machine‐learned molecular dynamics and machine‐learning‐based phase identification reveal the kinetically formed SEI at buried Li | Li6PS5Cl interfaces. The SEI is dominated by Li2S‐based anion‐substituted phases, while oxygen doping enhances SEI ionic conductivity.
Sojeong Yang   +6 more
wiley   +1 more source

Strategy used to study pH-dependent domain swapping process.

open access: yes, 2015
Strategy used to study pH-dependent domain swapping process.
Prashant Shingate (146643)   +2 more
core   +1 more source

Cation Diffusion‐Mediated Displaced Reaction‐Transformation in Green Steelmaking

open access: yesAdvanced Science, EarlyView.
The removal of O lattice atoms by environmental H2 at the surface of Fe3O4 results in Fe enrichment, driving the inward diffusion of Fe cations into the bulk. Through hopping between unoccupied and initially occupied sites, cation diffusion triggers a spatially displaced reaction‐transformation and drives subsequent dynamic phase transformations and ...
Guangyi Guo   +7 more
wiley   +1 more source

REVIEW 3D domain swapping: As domains continue to swap

open access: yes, 2002
Three-dimensional (3D) domain swapping creates a bond between two or more protein molecules as they exchange their identical domains. Since the term ‘3D domain swapping ’ was first used to describe the dimeric structure of diphtheria toxin, the database ...
David Eisenberg, Yanshun Liu
core  

Bio‐Inspired Bidirectional Winding Origami With Programmable Modular Reconfigurability and Scalability

open access: yesAdvanced Science, EarlyView.
A bio‐inspired bidirectional‐winding origami platform enables scalable and programmable deployable structures. Double axial folding inspired by earwig hindwings and Flasher‐based hybridization create modular multilayer architectures with diverse attainable winding angles under fixed boundary conditions.
Wenyao Zhang   +5 more
wiley   +1 more source

Enhanced Antifungal Activity of Engineered Proteins via Swapping between Thioredoxin H2 and H3

open access: yesApplied Sciences, 2019
Thioredoxins (Trxs) are proteins that act as antioxidants by facilitating the reduction of other proteins and are highly conserved in all organisms. Plant H-type Trx isoforms have different structures and perform multiple functions. Previous studies have
Jin-Young Kim   +8 more
doaj   +1 more source

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