Results 111 to 120 of about 1,858,101 (277)

A highly stable laccase obtained by swapping the second cupredoxin domain

Scientific Reports, 2018
The robustness of a high-redox potential laccase has been enhanced by swapping its second cupredoxin domain with that from another fungal laccase, which introduced a pool of neutral mutations in the protein sequence without affecting enzyme functionality.
Isabel Pardo, David Rodríguez-Escribano, Pablo Aza, Felipe de Salas, Angel T. Martínez, Susana Camarero   +5 more
doaj   +1 more source

Phonon‐Driven Tetrahedral Tilts Enable Ultralow Bulk Thermal Expansion and Interstitial Oxide‐Ion Migration in Phenacite Solid Electrolytes

Advanced Science, EarlyView.
This work demonstrates a design paradigm of phonon‐driven negative‐thermal‐expansion (NTE) flexible framework that exploits the intrinsic lattice flexibility of NTE frameworks to simultaneously suppress thermal expansion and activate oxide‐ion conduction, offering a promising strategy to mitigate TEC mismatch in solid‐state ionic devices.
Xiaohui Li, Lu liang, Qilong Shi, Xiaoge Wang, Cheng Li, Sihao Deng, Lunhua He, Qiang Li, Kun Lin, Xianran Xing, Xiaojun Kuang   +10 more
wiley   +1 more source

The N Terminus of the OB Domain of Telomere Protein TPP1 Is Critical for Telomerase Action

Cell Reports, 2018
Summary: Telomerase recruitment to telomeres and enzymatic processivity are mediated by TPP1, an essential component of telomere integrity and telomerase function.
Sherilyn Grill, Valerie M. Tesmer, Jayakrishnan Nandakumar   +2 more
doaj   +1 more source

3D Domain swapping, protein oligomerization, and amyloid formation. [PDF]

, 2001
In 3D domain swapping, first described by Eisenberg, a structural element of a monomeric protein is replaced by the same element from another subunit. This process requires partial unfolding of the closed monomers that is then followed by adhesion and ...
Jaskólski, Mariusz
core  

Domain-Swapping Switch Point in Ste20 Protein Kinase SPAK

, 2016
The related protein kinases SPAK and OSR1 regulate ion homeostasis in part by phosphorylating cation cotransporter family members. The structure of the kinase domain of OSR1 was determined in the unphosphorylated inactive form and, like some other Ste20 ...
Svetlana Earnest (1418557), Clinton A. Taylor (1664533), Samarpita Sengupta (1664527), Melanie H. Cobb (1418563), Yu-Chi Juang (1664530), Elizabeth J. Goldsmith (1664536)   +5 more
core   +1 more source

Flat Bands Induced by Non‐Collinear Antiferromagnetism in CoBi2Te4

Advanced Science, EarlyView.
Flat bands emerge at the edges of intrinsically non‐collinear antiferromagnetic CoBi2Te4 two‐septuple layers through the interplay of spin–orbit coupling–driven band inversion and non‐collinear antiferromagnetism, uncovering a previously unexplored mechanism for flat‐band formation and opening new opportunities for strongly correlated quantum states ...
Ziyuan Zhao, Yuefeng Yin, Jinxing Gu, Mark T. Edmonds, Nikhil V. Medhekar   +4 more
wiley   +1 more source

Molecular mechanism of substrate specificity for delta 6 desaturase from Mortierella alpina and Micromonas pusilla

Journal of Lipid Research, 2015
The ω6 and ω3 pathways are two major pathways in the biosynthesis of PUFAs. In both of these, delta 6 desaturase (FADS6) is a key bifunctional enzyme desaturating linoleic acid or α-linolenic acid.
Haisu Shi (史海粟), Haiqin Chen (陈海琴), Zhennan Gu (顾震南), Yuanda Song (宋元达), Hao Zhang (张灏), Wei Chen (陈卫), Yong Q. Chen (陈永泉)   +6 more
doaj   +1 more source

Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair

Advanced Science, EarlyView.
Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai, Pengchong Du, Zhaoyang Wang, Surilige, Rangga Fokta, Renjian Tan, Xiqing Zhao, Shuoyi Zhang, Yuecheng Wang, Yixin Zhang, Ziliang Fu, Rui Gong, Cheng Jiang, Yisheng He, Qiguang Wang, Renke Li, Khoon Lim, Junnan Tang, Xiaolin Cui   +18 more
wiley   +1 more source

Type 1 secretion necessitates a tight interplay between all domains of the ABC transporter

Scientific Reports
Type I secretion systems (T1SS) facilitate the secretion of substrates in one step across both membranes of Gram-negative bacteria. A prime example is the hemolysin T1SS which secretes the toxin HlyA.
Manuel T. Anlauf, Florestan L. Bilsing, Jens Reiners, Olivia Spitz, Eymen Hachani, Sander H. J. Smits, Lutz Schmitt   +6 more
doaj   +1 more source

A domain swap makes motor rings [PDF]

Science, 2016
Structural Biology Cells are packed with protein complexes. Cells must appropriately assemble these complexes while ensuring that component proteins do not aggregate prematurely. Baker et al. show that the FliG protein, part of the bacterial flagellar motor complex, can polymerize to forms rings by “domain swapping.” Domains within a single FliG can ...
openaire   +1 more source