Results 81 to 90 of about 255,903 (249)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Кваліфікація монопольного становища на ринках та підстави притягнення до відповідальності за зловживання ним

open access: yesТеорія і практика правознавства, 2018
Стаття присвячена розгляду теоретичних та практичних питань визначення монопольного становища суб’єктів господарюваннята застосування відповідальності до правопорушників за зловживання ним.
T. І. Shvydka
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Genetic Analysis of Grain Yield and Milling Quality Characters of Two Line Rice Hybrids [PDF]

open access: yesElectronic Journal of Plant Breeding, 2010
The experiment was laid out at Agricultural College and Research Institute, Madurai, Tamil Nadu. India and the materials for thisstudy consisted of three TGMS lines viz., TS 29, TS 6 and GD 98013 and 11 testers viz., ADT 39, ADT 41, Pusa Basmathi 1 ...
L. Mahalingam and N. Nadarajan
doaj  

Dominance as an accentual (prosodic) property of morphemes

open access: yesBaltistica, 2011
DOMINACIJA KAIP AKCENTINĖ (PROZODINĖ) MORFEMŲ SAVYBĖSantraukaTerminas dominacija kalbotyroje vartojamas iš seno įvairiomis reikšmėmis ir ne visada preciziškai. P.
Bonifacas Stundžia
doaj   +1 more source

Dominating set games [PDF]

open access: yesOperations Research Letters, 2004
This paper presents several representation theorems for the solubility of three cost allocation problems, which are presented as cooperative games. In each problem, a graph \(G = (V, E)\) is given along with a cost function: given \(S \subseteq V\), \(c(S)\) is the cost of \(k\)-dominating the vertices in \(S\), i.e., building a set \(K \subseteq V ...
openaire   +5 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

BIODIVERSITY ANALYSIS OF ECTOMYCORRHIZA BASED ON SLOPE IN SORONG NATURE PARK

open access: yesAgric
This study aims to identify and analyze the composition and distribution of ectomycorrhizal fungi in Sorong Nature Tourism Park. The method used was field observation or direct observation divided into five plots, namely in a special block of seed ...
Ponisri Ponisri, Anif Farida
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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