Results 191 to 200 of about 23,859 (257)

Biochemical profiling and symptomatology of androgen deficiency in males with cluster headache: A prospective case–control study

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background Cluster headache (CH) has historically been considered a male‐dominated disorder, suggesting a role for androgens in its pathophysiology. We aimed to evaluate hormone profiles and symptoms of androgen deficiency in CH.
Willemijn C. Naber   +7 more
wiley   +1 more source

HMGA2 is a highly sensitive marker for DICER1‐related tumours

open access: yesHistopathology, EarlyView.
Aims DICER1 is a microRNA biogenesis enzyme that, when mutated, results in a rewiring of the transcriptome. Germline pathogenic variants (PVs) in DICER1 result in DICER1‐related tumour predisposition (DRTP) characterized by 30 or more different, generally rare, paediatric or adolescent‐onset tumours.
Paul S. Thorner   +5 more
wiley   +1 more source

Pre-synchronization with GnRH or hCG enhances fertility outcomes of heat synch protocol in Holstein dairy cows across parities: A pilot study. [PDF]

open access: yesVet Anim Sci
Navidifar P   +7 more
europepmc   +1 more source

Clinical improvement and scalp microbiome restructuring following a 28‐day piroctone olamine shampoo intervention

open access: yesInternational Journal of Cosmetic Science, EarlyView.
A 28‐day clinical study in 41 individuals with oily dandruff showed that a piroctone olamine shampoo improved clinical symptoms while selectively reshaping the scalp bacterial and fungal microbiome toward a less dysbiotic profile. Abstract Objective To evaluate the clinical efficacy of a piroctone olamine–containing shampoo in individuals with oily ...
Spyridon Markos   +4 more
wiley   +1 more source

Early On‐Treatment Change in SALT as a Pragmatic Predictor of Ritlecitinib Response in Moderate‐To‐Severe Alopecia Areata: A Real‐World Cohort Study

open access: yesInternational Journal of Dermatology, EarlyView.
Ritlecitinib induced rapid clinical improvement in moderate‐to‐severe alopecia areata in real‐world practice. Early change in SALT at Week 12 strongly discriminated Week‐24 responders, supporting a pragmatic treat‐to‐target checkpoint, alongside improvements in clinician‐reported and patient‐reported outcomes and a favorable safety profile.
Giuseppe Gallo   +4 more
wiley   +1 more source

Clonal Hematopoiesis and CAR T Cell Therapy: From Biological Crosstalk to Clinical Implications

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Clonal hematopoiesis (CH) is increasingly recognized as a significant biological phenomenon in aging and cancer, marked by the expansion of hematopoietic stem and progenitor cells harboring somatic mutations in genes associated with myeloid neoplasms.
Wei Du   +4 more
wiley   +1 more source

When to consider an inborn error of immunity: clues for physicians

open access: yesInternal Medicine Journal, EarlyView.
Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley   +1 more source

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