Results 181 to 190 of about 50,631 (303)

AGPLO‐Driven Optimisation for Accurate Segmentation of Papillary Thyroid Carcinoma in Medical Imaging

open access: yesCAAI Transactions on Intelligence Technology, EarlyView.
ABSTRACT Papillary Thyroid Carcinoma (PTC) is the most prevalent thyroid malignancy, and accurate lesion segmentation is essential for clinical diagnosis and treatment planning. Metaheuristic optimisation algorithms have been widely used in Multi‐Threshold Image Segmentation (MTIS), but many existing methods suffer from an imbalance between global ...
Jing Ruan   +14 more
wiley   +1 more source

A Curious Case of Patterned Scarring Alopecia

open access: yes
JEADV Clinical Practice, EarlyView.
Jeta Buch   +3 more
wiley   +1 more source

Tapinarof as a Therapeutic Aryl Hydrocarbon Receptor‐Modulating Agent in the Treatment of Atopic Dermatitis

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory dermatitis underpinned by Type 2 inflammation driven by cytokines such as IL‐4 and IL‐13. It is characterized by skin barrier dysfunction, Th2 immune deviation, and pruritus. While biologics and oral Janus kinase (JAK) inhibitors demonstrate high therapeutic efficacy by targeting cytokines that ...
Gaku Tsuji   +7 more
wiley   +1 more source

Steatocystoma Multiplex Suppurativa—A Case Report and Review of Treatments

open access: yesAustralasian Journal of Dermatology, EarlyView.
ABSTRACT We report a case of Steatocystoma Multiplex Suppurativa (SMS), a rare condition that can mimic hidradenitis suppurativa (HS). We also present a review of the surgical and medical therapies, including potential biologic agents.
Justin Tam Vu, Alexis Daniel Lara Rivero
wiley   +1 more source

Management of Treatment Resistant EGFR Inhibitor‐Induced Papulopustular Exanthema With Isotretinoin and Dapsone

open access: yesAustralasian Journal of Dermatology, EarlyView.
ABSTRACT Background/Objectives Epidermal growth factor receptor inhibitors (EGFRi) commonly cause papulopustular exanthemas that may compromise the success of cancer therapy. While tetracyclines are first‐line treatment, data on alternative systemic agents for refractory cases remain limited.
Ishana Dixit   +2 more
wiley   +1 more source

The potential of human induced pluripotent stem cells for modelling diabetic wound healing in vitro [PDF]

open access: yes, 2018
Aasen   +150 more
core   +1 more source

Allergic Sensitization to Inhalant Allergens in the Upper Respiratory Tract—the B Cell Side

open access: yesAllergy, EarlyView.
ABSTRACT Allergic diseases are on the rise worldwide, driven by respiratory epithelial barrier dysfunction that promotes sensitization to inhalant allergens such as pollen, dust mites, pet dander, and fungal spores. These antigens trigger IgE‐mediated immune responses that lead to diseases such as allergic rhinitis (AR) and asthma.
Ola Grimsholm   +9 more
wiley   +1 more source

Autosomal Dominant Hyper‐IgE Syndrome Patients Retain IL10‐Producing preTh17‐Cells That Are Activated by Opportunistic Pathogens and Support IgE Production

open access: yesAllergy, EarlyView.
IL‐10 producing CCR6+Th‐cells are central memory T‐cells that express ROR‐γt and differentiate to Th17‐cells via an autocrine loop of STAT3‐activating cytokines (preTh17). STAT3‐deficient AD‐HIES patients lack Th17‐ and Tfh17‐cells but retain preTh17‐ and Th1/17‐cells.
Giorgia Moschetti   +18 more
wiley   +1 more source

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