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First Evidence of the Toxin Domoic Acid in Antarctic Diatom Species [PDF]

open access: yesToxins, 2021
The Southern Ocean is one of the most productive ecosystems in the world. It is an area heavily dependent on marine primary production and serving as a feeding ground for numerous seabirds and marine mammals.
Anna J. Olesen   +6 more
doaj   +4 more sources

Domoic Acid Toxicologic Pathology: A Review [PDF]

open access: yesMarine Drugs, 2008
Domoic acid was identified as the toxin responsible for an outbreak of human poisoning that occurred in Canada in 1987 following consumption of contaminated blue mussels [Mytilus edulis].
Olga M. Pulido
doaj   +7 more sources

Domoic Acid Epileptic Disease [PDF]

open access: yesMarine Drugs, 2014
Domoic acid epileptic disease is characterized by spontaneous recurrent seizures weeks to months after domoic acid exposure. The potential for this disease was first recognized in a human case study of temporal lobe epilepsy after the 1987 amnesic ...
John S. Ramsdell, Frances M. Gulland
doaj   +3 more sources

Development of a High-Sensitivity Electrochemical Biosensor for Domoic Acid and Its Cellular Impact on Human Stem and Neuron-Like Cells. [PDF]

open access: yesFood Sci Nutr
Integrated workflow of domoic acid (DA) detection in seafood using a high‐sensitivity electrochemical biosensor and subsequent evaluation of DA‐induced cellular responses. (A) DA monitoring in seafood: Marine samples (European anchovy and mussels from the Marmara and Black Sea) were collected, extracted using a 1:1 methanol/water mixture, and analyzed ...
Ekenel EQ   +10 more
europepmc   +2 more sources

Transcriptional Response in the Digestive Gland of the King Scallop (Pecten maximus) After the Injection of Domoic Acid [PDF]

open access: yesToxins, 2021
Some diatom species of the genus Pseudo-nitzschia produce the toxin domoic acid. The depuration rate of domoic acid in Pecten maximus is very low; for this reason, king scallops generally contain high levels of domoic acid in their tissues.
Pablo Ventoso   +5 more
doaj   +2 more sources

Domoic Acid Oxidative Effects on the Microalgae Phaeodactylum tricornutum [PDF]

open access: yesLife, 2023
Domoic acid (DA) is a natural occurring marine biotoxin. Oxidative stress generation due to DA exposure was reported in animals, but little is known on the phytoplankton community.
Joaquin Cabrera   +2 more
doaj   +2 more sources

Domoic Acid: A Review of Its Cytogenotoxicity Within the One Health Approach [PDF]

open access: yesAntioxidants
In this review, we toxicologically assessed the naturally occurring toxin domoic acid. We used the One Health approach because the impact of domoic acid is potentiated by climate change and water pollution on one side, and reflected in animal health ...
Goran Gajski   +3 more
doaj   +2 more sources

Marine toxin domoic acid alters nitrogen cycling in sediments [PDF]

open access: yesNature Communications, 2023
As a red tide algal toxin with intense neurotoxicity distributed worldwide, domoic acid (DA) has attracted increasing concerns. In this work, the integrative analysis of metagenome and metabolome are applied to investigate the impact of DA on nitrogen ...
Zelong Li   +5 more
doaj   +2 more sources

Climatic regulation of the neurotoxin domoic acid [PDF]

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2017
Significance We investigate regulation of domoic acid, a potent marine phycotoxin, at the climate scale. Due to the threat domoic acid can pose to public health, marine wildlife, and coastal economies, decades of laboratory experiments have examined controls on domoic acid production without reaching consensus on reliable toxin ...
Vera Trainer   +2 more
exaly   +3 more sources

Domoic acid biosynthesis and genome expansion in Nitzschia navis-varingica [PDF]

open access: yesmBio
Production of the neurotoxin domoic acid (DA) by benthic diatom Nitzschia navis-varingica poses considerable health and economic concerns. In this study, we employed whole genome sequencing and transcriptomic analyses of regionally distinct N.
Steffaney M. Wood-Rocca   +13 more
doaj   +2 more sources

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