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Domoic Acid Epileptic Disease [PDF]
Marine Drugs, 2014 Domoic acid epileptic disease is characterized by spontaneous recurrent seizures weeks to months after domoic acid exposure. The potential for this disease was first recognized in a human case study of temporal lobe epilepsy after the 1987 amnesic ...
John S. Ramsdell, Frances M. Gulland
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Domoic Acid Toxicologic Pathology: A Review [PDF]
Marine Drugs, 2008 Domoic acid was identified as the toxin responsible for an outbreak of human poisoning that occurred in Canada in 1987 following consumption of contaminated blue mussels [Mytilus edulis].
Olga M. Pulido
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Transcriptional Response in the Digestive Gland of the King Scallop (Pecten maximus) After the Injection of Domoic Acid [PDF]
Toxins, 2021 Some diatom species of the genus Pseudo-nitzschia produce the toxin domoic acid. The depuration rate of domoic acid in Pecten maximus is very low; for this reason, king scallops generally contain high levels of domoic acid in their tissues.
Pablo Ventoso +5 more
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Domoic Acid: A Review of Its Cytogenotoxicity Within the One Health Approach [PDF]
AntioxidantsIn this review, we toxicologically assessed the naturally occurring toxin domoic acid. We used the One Health approach because the impact of domoic acid is potentiated by climate change and water pollution on one side, and reflected in animal health ...
Goran Gajski +3 more
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Domoic Acid Oxidative Effects on the Microalgae Phaeodactylum tricornutum [PDF]
Life, 2023 Domoic acid (DA) is a natural occurring marine biotoxin. Oxidative stress generation due to DA exposure was reported in animals, but little is known on the phytoplankton community.
Joaquin Cabrera +2 more
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First Evidence of the Toxin Domoic Acid in Antarctic Diatom Species [PDF]
Toxins, 2021 The Southern Ocean is one of the most productive ecosystems in the world. It is an area heavily dependent on marine primary production and serving as a feeding ground for numerous seabirds and marine mammals.
Anna J. Olesen +6 more
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Marine toxin domoic acid alters nitrogen cycling in sediments [PDF]
Nature Communications, 2023 As a red tide algal toxin with intense neurotoxicity distributed worldwide, domoic acid (DA) has attracted increasing concerns. In this work, the integrative analysis of metagenome and metabolome are applied to investigate the impact of DA on nitrogen ...
Zelong Li +5 more
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Climatic regulation of the neurotoxin domoic acid [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2017 Significance We investigate regulation of domoic acid, a potent marine phycotoxin, at the climate scale. Due to the threat domoic acid can pose to public health, marine wildlife, and coastal economies, decades of laboratory experiments have examined controls on domoic acid production without reaching consensus on reliable toxin-producing ...
S Morgaine Mckibben +2 more
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Marine Drugs, 2013 Because domoic acid, a neurotoxic secondary metabolite produced by marine diatoms in the genus Pseudo-nitzschia, is hypothesized to be part of a high affinity iron uptake system, we investigated whether domoic acid could improve the competitive ability ...
Emily K. Prince +2 more
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Domoic acid biosynthesis and genome expansion in Nitzschia navis-varingica [PDF]
mBioProduction of the neurotoxin domoic acid (DA) by benthic diatom Nitzschia navis-varingica poses considerable health and economic concerns. In this study, we employed whole genome sequencing and transcriptomic analyses of regionally distinct N.
Steffaney M. Wood-Rocca +13 more
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