Results 21 to 30 of about 1,607 (170)
Marine Drugs, 2010 Domoic acid produced by marine algae has been shown to cause acute and chronic neurologic sequelae in Californian sea lions following acute or low-dose exposure.
Santokh Gill +5 more
doaj +1 more source
Neurological Disease Rises from Ocean to Bring Model for Human Epilepsy to Life
Toxins, 2010 Domoic acid of macroalgal origin was used for traditional and medicinal purposes in Japan and largely forgotten until its rediscovery in diatoms that poisoned 107 people after consumption of contaminated mussels.
John S. Ramsdell
doaj +1 more source
Toxicon: X, 2020 Numerous toxin-producing harmful algal (HAB) species occur in Florida's coastal waters. Exposure to these toxins has been shown to have sublethal effects in sea turtles.
Justin R. Perrault +5 more
doaj +1 more source
Angewandte Chemie, Volume 138, Issue 13, 23 March 2026.Kaitocephalin (KCP) is a neuroprotective fungal metabolite with a unique scaffold of amino acids linked via C–C bonds. Genome‐transcriptome analyses identified its biosynthetic gene cluster (kpb cluster) in Eupenicillium shearii. LC‐MS/MS profiling identified four new KCP‐related compounds.
Yukari Maeno +5 more
wiley +2 more sources
Toxins, 2019 Some species of the genus Pseudo-nitzschia produce the toxin domoic acid, which causes amnesic shellfish poisoning (ASP). Given that bivalve mollusks are filter feeders, they can accumulate these toxins in their tissues.
Pablo Ventoso +5 more
doaj +1 more source
A novel antibody-based biomarker for chronic algal toxin exposure and sub-acute neurotoxicity. [PDF]
PLoS ONE, 2012 The neurotoxic amino acid, domoic acid (DA), is naturally produced by marine phytoplankton and presents a significant threat to the health of marine mammals, seabirds and humans via transfer of the toxin through the foodweb.
Kathi A Lefebvre +10 more
doaj +1 more source
Neurobiology of Disease, 2012 Several studies have implicated the enzyme acetylcholinesterase (AChE) as well as several biometals in the pathogenesis of Alzheimer's disease (AD). A multifunctional molecule, the hybrid tacrine-8-hydroxyquinoline (named IQM-622), displays cholinergic ...
Desiree Antequera +7 more
doaj +1 more source
Molecules, 2020 This review considers the results of recent studies on marine excitatory amino acids, including kainic acid, domoic acid, dysiherbaine, and neodysiherbaine A, known as potent agonists of one of subtypes of glutamate receptors, the so-called kainate ...
Valentin A. Stonik, Inna V. Stonik
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Domoic Acid Impairment of Cardiac Energetics [PDF]
Toxicological Sciences, 2008 Excitatory mediated neuronal injury has been shown to involve a complex cascade of events. However, the associated cardiac damage reported in humans and marine animals following exposure to excitotoxins has not been well characterized. We hypothesized that the excitotoxin domoic acid can traverse cardiac cell membranes and elicit a deleterious effect ...
Alexandra, Vranyac-Tramoundanas +6 more
openaire +2 more sources
Current situation on analysis of marine toxins
Reviews in Analytical Chemistry, 2013 Marine toxins are a food safety concern worldwide. This review discusses current analytical methods for those toxins that are legally regulated in Europe, namely domoic acid, saxitoxin, okadaic acid, yessotoxin, pectenotoxin and azaspiracids, and all ...
Botana Ana M. +4 more
doaj +1 more source