Results 21 to 30 of about 6,252 (211)

Gene expression studies for the analysis of domoic acid production in the marine diatom Pseudo-nitzschia multiseries [PDF]

, 2013
Background: Pseudo-nitzschia multiseries Hasle (Hasle) (Ps-n) is distinctive among the ecologically important marine diatoms because it produces the neurotoxin domoic acid.
Bates, Stephen S., Boissonneault, Katie, Henningsen, Brooks M., Hogan, Deborah A., Housman, David E., Milton, Sean, Pelletier, Jerry, Robertson, Deborah L.   +7 more
core   +3 more sources

Differential Effects of Domoic Acid and E. coli Lipopolysaccharide on Tumor Necrosis Factor-α, Transforming Growth Factor-β1 and Matrix Metalloproteinase-9 Release by Rat Neonatal Microglia: Evaluation of the Direct Activation Hypothesis

Marine Drugs, 2007
The excitatory amino acid domoic acid is the causative agent of amnesic shellfish poisoning in humans. The in vitro effects of domoic acid on rat neonatal brain microglia were compared with E. coli lipopolysaccharide (LPS), a known activator of microglia
Sarath P. Gunasekera, Anne M. Romanic, Peer B. Jacobson, Michael J. Fay, Mary Hall, Renee Peksa, Marcio Guzman, Alejandro M. S. Mayer   +7 more
doaj   +1 more source

Dried blood spots in toxicology : from the cradle to the grave? [PDF]

, 2012
About a century after its first described application by Ivar Bang, the potential of sampling via dried blood spots (DBS) as an alternative for classical venous blood sampling is increasingly recognized.
De Kesel, Pieter, Ingels, Ann-Sofie, Lambert, Willy, Stove, Christophe   +3 more
core   +1 more source

Pseudo-nitzschia physiological ecology, phylogeny, toxicity, monitoring and impacts on ecosystem health [PDF]

, 2011
This paper is not subject to U.S. copyright. The definitive version was published in Harmful Algae 14 (2012): 271-300, doi:10.1016/j.hal.2011.10.025.Over the last decade, our understanding of the environmental controls on Pseudo-nitzschia blooms and ...
Adams, Adams, Almandoz, Almandoz, Altwein, Amato, Amato, Amato, Amato, Amorim, Amzil, Anderson, Anderson, Anne E. Thessen, Arzul, Arévalo, Bargu, Bargu, Bargu, Bargu, Bates, Bates, Bates, Bates, Bates, Bates, Bates, Bates, Bates, Bates, Bates, Baugh, Bejarano, Besiktepe, Bill, Blanco, Bogan, Bogan, Bogan, Boyd, Buck, Buck, Burns, Bursa, Busse, Calu, Campbell, Campbell, Carlson, Casteleyn, Casteleyn, Casteleyn, Casteleyn, Cendes, Cerino, Charles G. Trick, Chepurnov, Chepurnov, Cho, Churro, Cochlan, Cochlan, Cochlan, Coleman, Coleman, Coleman, Coleman, Costa, Costa, Costa, Costa, Cupp, Cusack, Dao, Davidovich, de Baar, de Baar, Del Rio, Dortch, Dortch, Doucette, Doucette, Douglas, Dyson, D’Alelio, EFSA, Ennaffah, Escalera, Evans, Evans, Evans, Evans, Fawcett, Fehling, Fehling, Fehling, Fehling, Fernandes, Fernandes, Ferrario, Ferrario, Ferrario, Fire, Fire, Fire, Fire, Forbes, Forbes, Fraga, Fritz, Fryxell, Fryxell, Gallacher, García-Mendoza, Garrison, Geitler, Gilgan, Gran, Granéli, Greenfield, Greenfield, Guannel, Gulland, Gárate-Lizárraga, HAB Report, Hagström, Hall, Hallegraeff, Hanic, Hansen, Hasle, Hasle, Hasle, Hasle, Hasle, Haya, Hernández-Becerril, Hernández-Becerril, Hernández-Becerril, Hillebrand, Hiltz, Holtermann, Horner, Horner, Horner, Horner, Horner, Howard, Huang, Hubbard, Illoul, Jackson, James, Jameson, Kaczmarska, Kaczmarska, Kaczmarska, Kaczmarska, Kawatsu, Kjæret, Klein, Kreuder, Kudela, Kudela, Kudela, Kudela, Kvitek, Lane, Lapworth, Leandro, Leandro, Lee, Lefebvre, Lefebvre, Liefer, Lincoln, Loureiro, Loureiro, Loureiro, Lund-Hansen, Lundholm, Lundholm, Lundholm, Lundholm, Lundholm, Lundholm, Lundholm, Lundholm, Lundholm, Lundholm, Lundholm, López-Rivera, MacFadyen, MacFadyen, MacIntyre, Mackenzie, Mafra, Mafra, Mafra, Mafra, Mafra, Maldonado, Maneiro, Mann, Marangoni, Marchetti, Marchetti, Marchetti, Martin, McDonald, Medina, Medlin, Mercado, Miller, Moniz, Moschandreou, Munilla, Méndez, Míguez, Naar, Nagasaki, Negri, Negri, Nicolaus G. Adams, Nina Lundholm, Novaczek, Nézan, Odebrecht, Olson, Orive, Orlova, Orsini, Orsini, Pan, Pan, Pan, Pan, Panggabean, Parsons, Parsons, Parsons, Penna, Perl, Pitcher, Powell, Pérez, Qi, Quijano-Scheggia, Quijano-Scheggia, Quijano-Scheggia, Rhodes, Rhodes, Rhodes, Rhodes, Rhodes, Ribalet, Rines, Rue, Sahraoui, Sahraoui, Santiago-Morales, Sar, Sarno, Sarno, Schandelmeier, Schnetzer, Scholin, Scholin, Schwacke, Sekula-Wood, Sekula-Wood, Shumway, Sierra-Beltrán, Sierra-Beltrán, Sierra-Beltrán, Silver, Skov, Smith, Smith, Sommer, Spatharis, Stehr, Stephen S. Bates, Stonik, Sun, Suárez-Isla, Tahri-Joutei, Takahashi, Taylor, Taylor, Teitelbaum, Tesson, Thessen, Thessen, Thessen, Trainer, Trainer, Trainer, Trainer, Trainer, Trainer, Trainer, Trainer, Trainer, Trainer, Trick, Trimborn, Tschochner, Turner, Tweddle, Twiner, Ujević, Uttal, Vale, Vale, Vale, Vale, Vera L. Trainer, Vigilant, Villac, Villac, Vrieling, Walz, Wekell, Wekell, Wells, Whyte, William P. Cochlan, Wohlgeschaffen, Work, Work, Zingone, Zou, Álvarez, Álvarez   +334 more
core   +1 more source

Proteomic Analysis of Plasma from California Sea Lions (Zalophus californianus) Reveals Apolipoprotein E as a Candidate Biomarker of Chronic Domoic Acid Toxicosis. [PDF]

PLoS ONE, 2014
Domoic acid toxicosis (DAT) in California sea lions (Zalophus californianus) is caused by exposure to the marine biotoxin domoic acid and has been linked to massive stranding events and mortality.
Benjamin A Neely, Jason A Ferrante, J Mauro Chaves, Jennifer L Soper, Jonas S Almeida, John M Arthur, Frances M D Gulland, Michael G Janech   +7 more
doaj   +1 more source

Domoic Acid Impairment of Cardiac Energetics [PDF]

Toxicological Sciences, 2008
Excitatory mediated neuronal injury has been shown to involve a complex cascade of events. However, the associated cardiac damage reported in humans and marine animals following exposure to excitotoxins has not been well characterized. We hypothesized that the excitotoxin domoic acid can traverse cardiac cell membranes and elicit a deleterious effect ...
Alexandra, Vranyac-Tramoundanas, Joanne C, Harrison, Andrew N, Clarkson, Mohit, Kapoor, Ian C, Winburn, D Steven, Kerr, Ivan A, Sammut   +6 more
openaire   +2 more sources

Cloning and Characterization of Glutamate Receptors in Californian Sea Lions (Zalophus californianus)

Marine Drugs, 2010
Domoic acid produced by marine algae has been shown to cause acute and chronic neurologic sequelae in Californian sea lions following acute or low-dose exposure.
Santokh Gill, Tracey Goldstein, Donna Situ, Tanja S. Zabka, Frances M. D. Gulland, Rudi W. Mueller   +5 more
doaj   +1 more source

Domoic acid as a developmental neurotoxin [PDF]

NeuroToxicology, 2010
Domoic acid (DomA) is an excitatory amino acid which can accumulate in shellfish and finfish under certain environmental conditions. DomA is a potent neurotoxin. In humans and in non-human primates, oral exposure to a few mg/kg DomA elicits gastrointestinal effects, while slightly higher doses cause neurological symptoms, seizures, memory impairment ...
COSTA, Lucio Guido, GIORDANO G., FAUSTMAN E. M.   +2 more
openaire   +3 more sources

Neurological Disease Rises from Ocean to Bring Model for Human Epilepsy to Life

Toxins, 2010
Domoic acid of macroalgal origin was used for traditional and medicinal purposes in Japan and largely forgotten until its rediscovery in diatoms that poisoned 107 people after consumption of contaminated mussels.
John S. Ramsdell
doaj   +1 more source

Diversity and toxicity of Pseudo-nitzschia species in Monterey Bay : perspectives from targeted and adaptive sampling [PDF]

, 2018
Author Posting. © The Author(s), 2018. This is the author's version of the work. It is posted here under a nonexclusive, irrevocable, paid-up, worldwide license granted to WHOI. It is made available for personal use, not for redistribution.
Birch, James M., Bowers, Holly A., Caron, David A., Doucette, Gregory J., Gellene, Alyssa G., Hayashi, Kendra, Hubbard, Katherine A., Kudela, Raphael M., Marin, Roman, Mikulski, Christina M., Ryan, John P., Scholin, Christopher A., Smith, G. Jason, Woods, April, Zhang, Yanwu   +14 more
core   +1 more source