Results 171 to 180 of about 6,252 (211)
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2018
In the summer of 1961, thousands of sooty shearwaters (Puffinus griseus), a medium-large long-winged seabird that feeds on krill, squid, and fish, converged on the shores of North Monterey Bay, California. The birds were found regurgitating anchovies, crashing through glass windows, attacking people, shrieking vocalization uncommon for this species ...
C. Cortinovis +4 more
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In the summer of 1961, thousands of sooty shearwaters (Puffinus griseus), a medium-large long-winged seabird that feeds on krill, squid, and fish, converged on the shores of North Monterey Bay, California. The birds were found regurgitating anchovies, crashing through glass windows, attacking people, shrieking vocalization uncommon for this species ...
C. Cortinovis +4 more
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Anaerobic biotransformation mechanism of marine toxin domoic acid
Journal of Hazardous Materials, 2022Domoic acid (DA) is a major marine neurotoxin, occurs frequently in most of the world's coastlines and seriously threatens ecosystem and public health. However, information on its biotransformation process in coastal anaerobic environments remains unclear. In this study, the underlying mechanism of anaerobic biotransformation of DA by marine consortium
Miaomiao, Du +5 more
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Ultraviolet spectrum of domoic acid
Canadian Journal of Chemistry, 1989The ultraviolet spectrum of aqueous domoic acid solutions has an intense absorption band, whose λmax shifts from 240.0 ± 0.3 nm at pH 1.3 to 244.7 ± 0.3 nm at pH 12.3. At the same time, its εmax increases from 24250 to 26700 L mol−1 cm−1. At pH 7 λmax is 242.8 ± 0.3 nm and εmax is 26035 ± 200 L mol−1 cm−1 Analysis of the variation of λmax and εmax ...
Michael Falk +2 more
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Domoic acid: a fascinating marine toxin
Environmental Toxicology and Pharmacology, 2001There are indications that toxic algal blooms are increasing because of pollution of coastal waters and worldwide shipping. This mini-review deals with the marine biotoxin domoic acid, also known as amnesic shellfish poison, and its main producing pennate diatom genus Pseudo-nitzschia (Bacillariophyceae).
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Perinatal Domoic Acid as a Neuroteratogen
2015In mammals, the period shortly before and shortly after birth is a time of massive brain growth, plasticity and maturation. It is also a time when the developing brain is exquisitely sensitive to insult, often with long-lasting consequences. Many of society's most debilitating neurological diseases arise, at least in part, from trauma around the time ...
Tracy A, Doucette, R Andrew, Tasker
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Domoic acid neurotoxicity in hippocampal slice cultures
Amino Acids, 2002The neurotoxicity of domoic acid was studied in 2-3 week old rat hippocampal slice cultures, derived from 7 day old rat pups. Domoic acid 0.1-100 microM was added to the culture medium for 48 hrs, alone or together with the glutamate receptor antagonists NS-102 (5-Nitro-6,7,8,9-tetrahydrobenzo[G]indole-2,3-dione-3-oxime), NBQX (2,3-dihydroxy-6-nitro-7 ...
Jakobsen, B., Tasker, A., Zimmer, J.
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Domoic acid induced seizure activity in rats
Neuroscience Letters, 1991Domoic acid, in increasing doses (10-300 pmol), was microinjected into the hippocampal CA3 region of rats. All rats consistently exhibited generalized bilateral electrical seizure discharge activity at 100 pmol of domoic acid. Seizure latency varied inversely with the dose of domoic acid in the range tested.
K, Dakshinamurti +2 more
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Chemistry of Domoic Acid, Isodomoic Acids, and Their Analogues
ChemInform, 2005AbstractFor Abstract see ChemInform Abstract in Full Text.
Clayden, Jonathan +2 more
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Ursolic acid improves domoic acid-induced cognitive deficits in mice
Toxicology and Applied Pharmacology, 2013Our previous findings suggest that mitochondrial dysfunction is the mechanism underlying cognitive deficits induced by domoic acid (DA). Ursolic acid (UA), a natural triterpenoid compound, possesses many important biological functions. Evidence shows that UA can activate PI3K/Akt signaling and suppress Forkhead box protein O1 (FoxO1) activity. FoxO1 is
Dong-mei, Wu +7 more
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Neuropathology of Excitatory Neurotoxins: The Domoic Acid Model
Toxicologic Pathology, 1990A novel type of intoxication in Canada in 1987 was traced to consumption of cultivated mussels contaminated with the excitotoxin domoic acid. Studies carried out in rats and monkeys revealed that parenterally administered domoic acid induces in rats neuroexcitatory phenomena culminating in seizures.
L, Tryphonas, F, Iverson
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