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Renal clearance of domoic acid in the rat
Food and Chemical Toxicology, 1993The renal clearance (Clr) of the seafood toxin domoic acid (DA) was investigated in the rat. Following cannulation of the right femoral artery, the left femoral vein and the bladder of anaesthetized rats, a single bolus injection of either [3H]DA, [14C]p-aminohippuric acid (PAH) or [3H]inulin was administered through the venous cannula.
C A, Suzuki, S L, Hierlihy
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[Domoic acid and human health].
Wei sheng yan jiu = Journal of hygiene research, 2010Domoic acid (DA), structurally related to glutamic and kainic acid, mainly generated by Pseudo nitzschia diatom. It often contaminates halobios such as fish and seashell and cause the Amnesic Shellfish Poisoning in human beings with the consumption of foods contaminated by DA. DA has been detected from seafoods worldwide.
Duo-Jia, Wu, Feng-Qi, Li
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[Domoic acid and glutamate receptors].
Wei sheng yan jiu = Journal of hygiene research, 2003Domoic acid is a kind of neurotoxin produced by diatoms and accumulated in food chain, which is harmful to the human health. The N-methyl-D-aspartate receptor and kainic acid/alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor could be activated by domoic acid. The concentration of the intracellular Ca2+ could be elevated, causing a series of
X, Chen, C, Wang
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Cases of poisoning caused by seafood are common around the world, especially in developing sea and ocean coastal countries. Domoic acid, which became popular with the mass poisoning case in the 1980s, was actually used in alternative treatment practices. Poisoning caused by domoic acid is called amnesic shellfish poisoning. Although poisoning caused by
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Neurologic Sequelae of Domoic Acid Intoxication Due to the Ingestion of Contaminated Mussels
New England Journal of Medicine, 1990Robert J Zatorre, Albert H Gjedde
exaly

