Results 51 to 60 of about 12,409,454 (287)

Acceptance of deceased donor livers in the United Kingdom – development of a liver “donor utilisation index”

Transplant International
Published Donor Risk Indices are often used to estimate the risk associated with transplanting a donor liver. Such indices have been constructed by considering only livers that are transplanted and estimating the risk of graft loss or patient death ...
Jennifer Mehew, Helen Thomas, Peter Friend, Peter Friend, Simon Knight, Simon Knight   +5 more
doaj   +1 more source

Lung Transplantation from Donors after Circulatory Death Using Portable Ex Vivo Lung Perfusion

Canadian Respiratory Journal, 2015
BACKGROUND: Donation after circulatory death is a novel method of increasing the number of donor lungs available for transplantation. Using organs from donors after circulatory death has the potential to increase the number of transplants performed.
Sabin Bozso, Vishnu Vasanthan, Jessica GY Luc, Katie Kinaschuk, Darren Freed, Jayan Nagendran   +5 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Theological Reflections on Donation After Circulatory Death: The Wisdom of Paul Ramsey and Moshe Feinstein

, 2008
Due to the worldwide shortage of organs for transplantation, there has been an increased use of organs obtained after circulatory death alone. A protocol for this procedure has recently been approved by a major transplant consortium.
Jotkowitz, A.
core   +1 more source

Promising Results of Kidney Transplantation From Donors Following Euthanasia During 10-Year Follow-Up: A Nationwide Cohort Study

Transplant International
The outcome of kidneys transplanted following organ donation after euthanasia (ODE) remains unclear. This study analyzed all kidney transplantations in the Netherlands from January 2012 to December 2021, comparing the outcomes following ODE, donation ...
Charlotte Susanna, Charlotte Susanna, Nathalie van Dijk, Wim de Jongh, Hanne Verberght, Hanne Verberght, Hanne Verberght, Walther van Mook, Walther van Mook, Walther van Mook, Jan Bollen, Bas van Bussel, Bas van Bussel, Bas van Bussel   +13 more
doaj   +1 more source

Organ donation after circulatory death as compared with organ donation after brain death in Switzerland – an observational study

Swiss Medical Weekly, 2022
AIMS OF THE STUDY: Organ donation after circulatory death (DCD) was reintroduced in Switzerland in 2011 and accounts for a third of deceased organ donors today.
Andreas Elmer, Mara-Lisa Rohrer, Christian Benden, Nathalie Krügel, Franziska Beyeler, Franz F Immer   +5 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Uncontrolled Donation Potential After Circulatory Death in Slovenia Could Lead to More Organ Donations: Extrapolation of SiOHCA Study Data

Inquiry: The Journal of Health Care Organization, Provision, and Financing
Out-of-hospital cardiac arrest is one of the major health challenges faced by developed countries. Donation after circulatory death is a process of retrieving organs from individuals whose death has been confirmed by circulatory or respiratory criteria ...
Domen Kulovec MD, Luka Petravić MD, Rok Miklič, Evgenija Burger BSc, Urša Keše BSc, Eva Poljanšek MD, Gašper Tomšič MSc, Tilen Pintarič AAS, Miguel Faria Lopes BSc, Ema Turnšek MSc, Andrej Gadžijev MD, Matej Strnad MD, PhD   +11 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Kidney transplantation from uncontrolled donation after circulatory death donors maintained by nECMO has long-term outcomes comparable to standard criteria donation after brain death

, 2018
Uncontrolled donation after circulatory death (uDCD) increases organ availability for kidney transplant (KT) with short-term outcomes similar to those obtained from donation after brain death (DBD) donors.
Justo Alonso, Iago, Molina Martín, María, Rodríguez Antolín, Alfredo, Hernández Martínez, Eduardo Rafael, Guerrero Ramos, Félix, González Monte, Esther, Andrés Belmonte, Amado, Morales Ruiz, Enrique, Pamplona Casamayor, Manuel, Cavero, Teresa, Fernández Ruiz, Mario, Villar, Alicia, Cabrera, Jimena, Praga Terente, Manuel, Chico, Mario, Polanco, Natalia, Hernández Vicente, Ana, Gutiérrez Martínez, Eduardo, Rosa, Federico de la   +18 more
core   +1 more source