Results 131 to 140 of about 43,876 (313)
Evaluation the effect of Donepezil on Cerebral Blood Flow Velocity in Alzheimer's Disease
مجله دانشکده پزشکی اصفهان, 2010 Background: The main cause of Alzheimer's disease (AD) is loss of cholinergic function. So, the choice strategy of therapy is to increase the level of acetylcholine (Ach) in the brain of by acetylcholinesterase inhibitors (AchEIs) such as Donepezil. This
Abbas Ghorbani +3 more
doaj
Clinical neuropharmacology, 2019 Purpose Donepezil is known to increase cholinergic synaptic transmission in Alzheimer disease (AD), although how it affects cortical brain activity and how it consequently affects brain functions need further clarification. To investigate the therapeutic
Jianan Cheng, Hua Yang, Jiangtao Zhang
semanticscholar +1 more source
Light‐Activated Pharmacological Tools for Exploring the Cholinergic System
Medicinal Research Reviews, Volume 45, Issue 4, Page 1251-1274, July 2025.ABSTRACT Cholinergic transmission plays a critical role in both the central and peripheral nervous systems, affecting processes such as learning, memory, and inflammation. Conventional cholinergic drugs generally suffer from poor selectivity and temporal precision, leading to undesired effects and limited therapeutic efficacy. Photopharmacology aims to
Alessio Colleoni +5 more
wiley +1 more source
全身麻酔下家兎を用いたブプレノルフィンによる中枢性呼吸抑制に対するドネペジルによる拮抗作用 [PDF]
, 2016 Buprenorphine is a mixed opioid receptor agonist-antagonist used in acute and chronic pain management. Although this agent\u27s analgesic effect increases in a dose-dependent manner, buprenorphine-induced respiratory depression shows a marked ceiling ...
櫻庭 茂樹
core +1 more source
Low-Cost Portable Light Therapy for Alzheimer's Patients [PDF]
, 2019 This paper provides an overview of the information and research conducted that ushered the creation and innovation of a low-cost portable light therapy device to help treat Alzheimer’s patients.
Arasu, Melghi, Zoghi, Ben, Zoghi, Sara
core +1 more source
Donepezil increases resistance to induced seizures in a mouse model of Dravet syndrome
Annals of Clinical and Translational Neurology, 2019 De novo loss‐of‐function mutations in SCN1A are the main cause of Dravet syndrome, a catastrophic encephalopathy characterized by recurrent early‐life febrile seizures, a number of other afebrile seizure types that are often refractory to treatment, and ...
Jennifer C. Wong +2 more
semanticscholar +1 more source
Humility and Medicine, Lessons Learned: Perhaps the Fifth Ethics Principle
Journal of the American Geriatrics Society, EarlyView.
Michael Gordon
wiley +1 more source
Association of preeclampsia with long‐term risk of neurodegenerative disorders
Pregnancy, Volume 1, Issue 4, July 2025.Objective Preeclampsia (PE) is a common complication of pregnancy linked to increased lifetime risk of multiple comorbidities. However, the link between PE and development of adverse neurologic conditions is still poorly understood. Our objective was to investigate the risk of neurodegenerative disorders for women with PE compared to those without PE ...
Maria Bazan +3 more
wiley +1 more source
Bayesian Value-of-Information Analysis: An Application to a Policy Model of Alzheimer's Disease [PDF]
A framework is presented which distinguishes the conceptually separate decisions of which treatment strategy is optimal from the question of whether more information is required to inform this choice in the future.
K. Claxton +3 more
core
Emerging pharmacotherapy for cancer patients with cognitive dysfunction [PDF]
, 2013 Advances in the diagnosis and multi-modality treatment of cancer have increased survival rates for many cancer types leading to an increasing load of long-term sequelae of therapy, including that of cognitive dysfunction.
A Parachikova +67 more
core +2 more sources