Results 81 to 90 of about 33,626 (230)

(Poly)Borylated Species as Modern Reactive Groups toward Unusual Synthetic Applications

Angewandte Chemie, Volume 138, Issue 10, 2 March 2026.
In this review, we spotlight recent breakthroughs in α‐polyboron‐substituted carbon‐centered intermediates (carbanion, carbocation, radical, and carbene) and polyborylated alkenes. By bridging fundamental reactivity with the application potential of these extraordinary species, we hope this review will serve as a roadmap for harnessing these unique ...
Nadim Eghbarieh, Nicole Hanania, Pinaki Nad, Tipu Alam, Tamir Kish, Ahmad Masarwa   +5 more
wiley   +2 more sources

A double-blind placebo-controlled cross-over clinical trial of DONepezil In Posterior cortical atrophy due to underlying Alzheimer's Disease: DONIPAD study. [PDF]

, 2018
BACKGROUND: The study investigated whether donepezil exerts symptomatic benefit in patients with posterior cortical atrophy (PCA), an atypical variant of Alzheimer's disease. METHODS: A single-centre, double-blind, placebo-controlled, cross-over clinical
A Burns, B Jones, Basil H. Ridha, Christopher Frost, Dawn Cutler, DF Tang-Wai, DM Baxter, E Kim, EK Warrington, Elizabeth K. Warrington, I Blasko, Jane Douglas, JR Willison, JS Ross, M Jackson, M Singer, Martin N. Rossor, MF Folstein, MF Mendez, Norah Epie, RD Pratt, Riitta Kukkastenvehmas, Sebastian Crutch, SG Di Santo, SJ Crutch, SL Rogers, Suzie Barker, William Knight, Y Kitabayashi   +28 more
core   +2 more sources

Association of Palliative Care Initiation With Acute Healthcare Utilization Among Community‐Dwelling Adults Living With Dementia

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Objectives To measure the association between initiating palliative care using the combined criteria of short survival expectations and increased care needs with acute healthcare utilization among community‐dwelling people living with dementia. Design A population‐level propensity‐based overlap‐weighted cohort study.
Kieran L. Quinn, Thérèse A. Stukel, Michael Pugliese, Allan S. Detsky, George Heckman, Mariam Toluwalashe Omilabu, Nathan M. Stall, Desiree Vaz, Colleen Webber, Peter Tanuseputro, Sarina Isenberg   +10 more
wiley   +1 more source

Emerging pharmacotherapy for cancer patients with cognitive dysfunction [PDF]

, 2013
Advances in the diagnosis and multi-modality treatment of cancer have increased survival rates for many cancer types leading to an increasing load of long-term sequelae of therapy, including that of cognitive dysfunction.
A Parachikova, A Prakash, B Gagnon, BP Daly, C Cunningham, C Gottesmann, CD Aluise, CJ Nelson, CM Reid, D Greene-Schloesser, D Holmes, D Jaturapatporn, D Kim, David M Ashley, DD Correa, EE Lower, EG Shaw, EJ Jacobs, EM Yazlovitskaya, ES Yang, F Joly, F Xia, Fiona M Ahlberg, G Winocur, G Winocur, H Cimarosti, HG Mar Fan, HM Conklin, J Kim, J Lindsay, JC Adair, JH Kang, JM Leoutsakos, JS Wefel, JS Wefel, JS Wefel, Justin Davis, K Gehring, K Hermelink, K Hermelink, L Blackhall, L Lundorff, M Batalo, M Berbee, M Berk, M Inouye, M Khasraw, M Khasraw, M Khasraw, MC Janelsins, ME Robbins, Michael Berk, MJR Howes, Mustafa Khasraw, N Biglia, N Volkow, PD Brown, RK Mulhern, S Kohli, SJ Thompson, SM Castellino, T Scammell, TE Wilens, TM Engber, V Dutta, V Tiwari, W Lasheen, Y Liu   +67 more
core   +2 more sources

Adaptation of DETECT for Use in Home‐Based Primary Care: Clinician Perspectives

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Elder mistreatment (EM) is pervasive yet under‐identified. The Detection of Elder abuse Through Emergency Care Technicians (DETECT) tool was developed to improve EM identification and reporting among emergency medical technicians. This study explores clinician perspectives on adapting DETECT for use in home‐based primary care (HBPC).
Kristin Lees Haggerty, Randi Campetti, Olanike Ojelabi, Jason Burnett, Melvin Livingston, Carolyn Pickering, Rania Abdelkhaleq, Thomas K. M. Cudjoe, Deborah G. Freeland, Julia Hiner, Maria Yefimova, Brad Cannell   +11 more
wiley   +1 more source

Obsessive–compulsive disorder induced by donepezil in a patient with Alzheimer's disease

PCN Reports
Background Donepezil, an acetylcholinesterase inhibitor commonly used to treat Alzheimer's disease (AD), is generally well tolerated. There have been no previous reports on donepezil‐induced obsessive–compulsive disorder (OCD).
Kohei Echizen, Daisuke Hirose
doaj   +1 more source

A Retrospective National Cohort Study of Trends in Mechanical Ventilation Among Veterans Living With Dementia, 2010–2019

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Despite longstanding concern about an increase in use of invasive mechanical ventilation among persons living with dementia (PLWD), no studies have examined trends in mechanical ventilation use among PLWD in Veterans Affairs (VA) facilities. In this study, we aimed to (1) identify recent trends in use of mechanical ventilation among
Judith B. Vick, Maren K. Olsen, Graham Cummin, Theodore S. Z. Berkowitz, Jessica E. Ma, Megan Shepherd‐Banigan, Brystana G. Kaufman, Catherine Stanwyck, Jennifer L. Wolff, Cynthia M. Boyd, Andrew B. Cohen, Terri R. Fried, Stephanie K. Nothelle   +12 more
wiley   +1 more source

Clinical efficacy and safety of donepezil in the treatment of Alzheimer’s disease in Chinese patients

Clinical Interventions in Aging, 2018
Nan Zhang,1,2 Marc L Gordon3,4 1Department of Neurology, Tianjin Medical University General Hospital, Tianjin Neurological Institute, Tianjin, People’s Republic of China; 2Department of Neurology and Neurosurgery, Tianjin Medical University ...
Zhang N, Gordon ML
doaj  

An Investigation of the Efficacy of Curcumin for Treatment of Alzheimer\u27s Disease [PDF]

, 2016
Curcumin is the primary curcuminoid found in the rhizome of the turmeric plant (Curcuma longa), responsible for the spice’s distinctive yellow color. Research conducted within the past two decades suggests that the compound may be an effective treatment ...
Patel, Parantap
core   +1 more source

Evaluating High-Dose Rivastigmine Patch in Severe Alzheimer’s Disease: Analyses with Concomitant Memantine Usage as a Factor [PDF]

, 2015
Background: ACTION, a 24-week, prospective, randomized, parallel-group, double-blind study in patients with severe Alzheimer’s disease (AD), demonstrated significant efficacy of 13.3 mg/24 h versus 4.6 mg/24 h rivastigmine patch on the Severe Impairment ...
Farlow, Martin R., Grossberg, George T., Meng, Xiangyi, Velting, Drew M.   +3 more
core   +1 more source