Results 61 to 70 of about 33,915 (216)
Phytotherapy Research, EarlyView.Doxorubicin induces cardiac and skeletal muscle atrophy by upregulating E3 ubiquitin ligases, inhibiting myogenic regulatory factors, and activating necroptosis. Cardiac atrophy can further exacerbate cardiotoxicity. 6‐Shogaol negatively regulates these processes and attenuates doxorubicin‐induced cardiac and skeletal muscle atrophy.
Xipeng Sun +5 more
wiley +1 more source
Auditory training changes temporal lobe connectivity in 'Wernicke's aphasia': a randomised trial [PDF]
, 2017 INTRODUCTION: Aphasia is one of the most disabling sequelae after stroke, occurring in 25%-40% of stroke survivors. However, there remains a lack of good evidence for the efficacy or mechanisms of speech comprehension rehabilitation.
Crinion, J +5 more
core +3 more sources
Acta Ophthalmologica, EarlyView.Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen +3 more
wiley +1 more source
Frontiers in Neuroscience, 2020 Donepezil is a potent acetylcholinesterase inhibitor, largely used worldwide to alleviate cognitive symptoms in Alzheimer’s disease (AD). Beyond the widely described neuronal impact of donepezil, it was recently shown that targeting connexins, the ...
Benjamin Vidal +9 more
doaj +1 more source
Adaptation of DETECT for Use in Home‐Based Primary Care: Clinician Perspectives
Journal of the American Geriatrics Society, EarlyView.ABSTRACT Background Elder mistreatment (EM) is pervasive yet under‐identified. The Detection of Elder abuse Through Emergency Care Technicians (DETECT) tool was developed to improve EM identification and reporting among emergency medical technicians. This study explores clinician perspectives on adapting DETECT for use in home‐based primary care (HBPC).
Kristin Lees Haggerty +12 more
wiley +1 more source
Donepezil, anti-Alzheimer's disease drug, prevents cardiac rupture during acute phase of myocardial infarction in mice. [PDF]
PLoS ONE, 2011 BACKGROUND: We have previously demonstrated that the chronic intervention in the cholinergic system by donepezil, an acetylcholinesterase inhibitor, plays a beneficial role in suppressing long-term cardiac remodeling after myocardial infarction (MI).
Mikihiko Arikawa +4 more
doaj +1 more source
A case of Diogenes Syndrome [PDF]
, 2013 Diogenes Syndrome is a syndrome of extreme selfneglect, domestic squalor, excessive hoarding, social withdrawal and refusal of all help and lack of concern regarding one’s personal residential situation. A case report of an 83 year old lady with mild
Ferry, Peter
core
The Effect of the Association between Donepezil and Choline Alphoscerate on Behavioral Disturbances in Alzheimer's Disease: Interim Results of the ASCOMALVA Trial [PDF]
, 2017 BACKGROUND: Behavioral and psychological symptoms of dementia (BPSD) are a group of psychological reactions, psychiatric symptoms, and behaviors commonly found in Alzheimer's disease (AD).
Amenta, Francesco +6 more
core +1 more source
Pharmacological Management of Lewy Body Dementia: A Systematic Review and Meta-Analysis. [PDF]
, 2015 OBJECTIVE: The authors examined research on effects, costs, and patient and caregiver views of pharmacological management strategies for Lewy body dementia.
Cambridge, Victoria +9 more
core +2 more sources
Journal of the American Geriatrics Society, EarlyView.ABSTRACT Background The long‐term care (LTC) Data Cooperative is a National Institute on Aging‐funded data resource that links skilled nursing facility (SNF) electronic health record (EHR) data with Medicare and Medicaid claims for use in comparative effectiveness and interventional research.
Stephanie M. Kissam +8 more
wiley +1 more source