Results 81 to 90 of about 21,434 (231)
Pharmacist-based Donepezil Outpatient Consultation Service to improve medication persistence
Norio Watanabe,1,2 Keiko Yamamura,3 Yusuke Suzuki,4 Hiroyuki Umegaki,4 Katsuro Shigeno,5 Ryo Matsushita,1 Yoshimichi Sai,1 Ken-ichi Miyamoto,1 Kiyofumi Yamada61Department of Clinical Pharmacy, Graduate School of Natural Science and Technology, Kanazawa ...
Shigeno K +8 more
core
Durable recovery from amblyopia with donepezil
An elevated threshold for neuroplasticity limits visual gains with treatment of residual amblyopia in older children and adults. Acetylcholinesterase inhibitors (AChEI) can enable visual neuroplasticity and promote recovery from amblyopia in adult mice ...
Eric D. Gaier +5 more
core +1 more source
Clinical Observation on Basal Ganglia Aphasia after Stroke Treated by Donepezil
Objective:To evaluate the curative effect of donepezil on basal ganglia aphasia after stroke.Methods:A total of 37 patients with basal ganglia aphasia after stroke were randomly assigned to donepezil group (n=19) and control group (n=18).
Xi CHENG +5 more
doaj
Abstract Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder driven by intersecting pathological processes. Persistent attrition in AD drug‐development pipelines highlights the limited clinical impact of single‐target therapies and has increased interest in multi‐target approaches acting on shared biological hubs.
Humberto Martínez‐Orozco +4 more
wiley +1 more source
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale +5 more
wiley +1 more source
Evaluation of the antioxidant activity of donepezil - in vitro study
Background: Donepezil is a cerebroselective anticholinesterase which is majorly used for memory enhancement in Alzheimers disease (AD). The main action is through increasing central cholinergic neurotransmission but also indicated that it protects ...
Vinay Munishamappa +3 more
doaj +1 more source
Thiosemicarbazones generally show higher MAO‐B inhibitory potential than their corresponding semicarbazones, and particularly T6 is the most potent, which contains R = H and X = S in its Tail Unit, with an IC50 value of 6.45 µM with SI of 3.6. ABSTRACT Twenty semicarbazone and thiosemicarbazone derivatives (T1–T20) were synthesized and evaluated for ...
Sandeep Bindra +11 more
wiley +1 more source
Donepezil for vascular cognitive impairment
Background Vascular disease is the second commonest cause of dementia after Alzheimer's disease. There are difficulties in classifying patients with this type of cognitive impairment owing to varied clinical presentation and different types of arterial ...
Malouf, Reem, Birks, Jacqueline
core +1 more source
Effects of Donepezil on the Musculoskeletal System in Female Rats
The extension of human life makes it more and more important to prevent and treat diseases of the elderly, including Alzheimer’s disease (AD) and osteoporosis.
Marcin Trawczyński +4 more
core +1 more source
Aim: To evaluate the efficacy and safety of donepezil plus natural hirudin in patients with mild-to-moderate Alzheimer's Disease. Methods: In the 20-week, randomized, open-label and controlled study, 84 patients received either donepezil (5 mg/day for ...
De-qiang Li, Yu-ping Zhou, Han Yang
doaj

