Results 81 to 90 of about 21,434 (231)

Pharmacist-based Donepezil Outpatient Consultation Service to improve medication persistence

open access: yes, 2012
Norio Watanabe,1,2 Keiko Yamamura,3 Yusuke Suzuki,4 Hiroyuki Umegaki,4 Katsuro Shigeno,5 Ryo Matsushita,1 Yoshimichi Sai,1 Ken-ichi Miyamoto,1 Kiyofumi Yamada61Department of Clinical Pharmacy, Graduate School of Natural Science and Technology, Kanazawa ...
Shigeno K   +8 more
core  

Durable recovery from amblyopia with donepezil

open access: yes, 2023
An elevated threshold for neuroplasticity limits visual gains with treatment of residual amblyopia in older children and adults. Acetylcholinesterase inhibitors (AChEI) can enable visual neuroplasticity and promote recovery from amblyopia in adult mice ...
Eric D. Gaier   +5 more
core   +1 more source

Clinical Observation on Basal Ganglia Aphasia after Stroke Treated by Donepezil

open access: yes康复学报, 2015
Objective:To evaluate the curative effect of donepezil on basal ganglia aphasia after stroke.Methods:A total of 37 patients with basal ganglia aphasia after stroke were randomly assigned to donepezil group (n=19) and control group (n=18).
Xi CHENG   +5 more
doaj  

Redirecting Alzheimer's disease therapeutics: Multitarget drugs and complementary non‐pharmacological strategies

open access: yesAlzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder driven by intersecting pathological processes. Persistent attrition in AD drug‐development pipelines highlights the limited clinical impact of single‐target therapies and has increased interest in multi‐target approaches acting on shared biological hubs.
Humberto Martínez‐Orozco   +4 more
wiley   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1787-1808, June 2026.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale   +5 more
wiley   +1 more source

Evaluation of the antioxidant activity of donepezil - in vitro study

open access: yesNational Journal of Physiology, Pharmacy and Pharmacology, 2019
Background: Donepezil is a cerebroselective anticholinesterase which is majorly used for memory enhancement in Alzheimer’s disease (AD). The main action is through increasing central cholinergic neurotransmission but also indicated that it protects ...
Vinay Munishamappa   +3 more
doaj   +1 more source

Monoamine Oxidase and Cholinesterase Inhibition Profiles of Semicarbazone and Thiosemicarbazone Derivatives

open access: yesChemistry &Biodiversity, Volume 23, Issue 6, June 2026.
Thiosemicarbazones generally show higher MAO‐B inhibitory potential than their corresponding semicarbazones, and particularly T6 is the most potent, which contains R = H and X = S in its Tail Unit, with an IC50 value of 6.45 µM with SI of 3.6. ABSTRACT Twenty semicarbazone and thiosemicarbazone derivatives (T1–T20) were synthesized and evaluated for ...
Sandeep Bindra   +11 more
wiley   +1 more source

Donepezil for vascular cognitive impairment

open access: yes, 2004
Background Vascular disease is the second commonest cause of dementia after Alzheimer's disease. There are difficulties in classifying patients with this type of cognitive impairment owing to varied clinical presentation and different types of arterial ...
Malouf, Reem, Birks, Jacqueline
core   +1 more source

Effects of Donepezil on the Musculoskeletal System in Female Rats

open access: yes, 2023
The extension of human life makes it more and more important to prevent and treat diseases of the elderly, including Alzheimer’s disease (AD) and osteoporosis.
Marcin Trawczyński   +4 more
core   +1 more source

Donepezil Combined with Natural Hirudin Improves the Clinical Symptoms of Patients with Mild-to-Moderate Alzheimer's Disease: A 20-Week Open-Label Pilot Study

open access: yesInternational Journal of Medical Sciences, 2012
Aim: To evaluate the efficacy and safety of donepezil plus natural hirudin in patients with mild-to-moderate Alzheimer's Disease. Methods: In the 20-week, randomized, open-label and controlled study, 84 patients received either donepezil (5 mg/day for ...
De-qiang Li, Yu-ping Zhou, Han Yang
doaj  

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