Results 81 to 90 of about 17,393 (175)

Single dose pharmacokinetics of the novel transdermal donepezil patch in healthy volunteers

Drug Design, Development and Therapy, 2015
Yo Han Kim,1 Hee Youn Choi,1 Hyeong-Seok Lim,1 Shi Hyang Lee,1 Hae Sun Jeon,1 Donghyun Hong,2 Seong Su Kim,2 Young Kweon Choi,2 Kyun-Seop Bae1 1Department of Clinical Pharmacology and Therapeutics, College of Medicine, University of Ulsan, Asan Medical ...
Kim YH, Choi HY, Lim HS, Lee SH, Jeon HS, Hong D, Kim SS, Choi YK, Bae KS   +8 more
doaj  

Revisiting the Metabolism of Donepezil in Rats Using Non-Targeted Metabolomics and Molecular Networking

Pharmaceutics
Background/Objectives: Although donepezil, a reversible acetylcholinesterase inhibitor, has been in use since 1996, its metabolic characteristics remain poorly characterized.
Eun-Ji Park, Eui-Hyeon Kim, Ki-Young Kim, Ji-Hyeon Jeon, Im-Sook Song, So-Young Park, Kwang-Hyeon Liu   +6 more
doaj   +1 more source

The effect of canagliflozin on hippocampal dendrite morphology in a model of Alzheimer's disease induced by intracerebroventricular injection of streptozotocin. [PDF]

Brain Struct Funct
Yazi S, Ozen B, Buldu B, Yalcin E, Karakose O, Cakmak O, Somunkiran S, Yananli HR, Sehirli US, Kirazli O.   +9 more
europepmc   +1 more source

Entropy estimation in acetylcholinesterase-donepezil interaction through topological indices: a graph theoretical perspective. [PDF]

Front Chem
Gayathri KB, Roy S, Jyothish K.
europepmc   +1 more source

Age-Dependent Remodeling of the Sciatic Nerve Proteome in 5xFAD Mice Can Be Attenuated by Exercise or Donepezil Treatment to Maintain Neuromuscular Function. [PDF]

Aging Cell
Brisendine MH, Nieves-Esparcia DQ, Willoughby OS, Brown B, Brown JR, Braxton DS, Henry SN, McCoin CS, Thyfault JP, Morris JK, Poelzing S, Grange RW, Jarome TJ, Najt CP, Drake JC.   +14 more
europepmc   +1 more source

Donepezil ameliorates fatigue and depression in PASC patients with HHV-6B SITH-1-induced acetylcholine deficiency. [PDF]

Front Pharmacol
Oka N, Nakamura K, Hirahata K, Ishii A, Yamakawa K, Ie K, Goto T, Shimada K, Fujitani S, Kondo K.   +9 more
europepmc   +1 more source

The Acetylcholine Esterase Inhibitor Donepezil Increases Dopamine Levels in the Nucleus Accumbens and Blocks the Alcohol Deprivation Effect in Rats. [PDF]

Addict Biol
Loftén A, Danielsson K, Adermark L, Söderpalm B, Ericson M.   +4 more
europepmc   +1 more source

Comparative evaluation of donepezil-loaded polymeric and liposomal nanoparticles for Alzheimer's disease: biocompatibility, drug release kinetics, and cellular uptake study. [PDF]

RSC Adv
Torossian T, Abla KK, Dakour J, Assi S, Karam M, Mhanna R.   +5 more
europepmc   +1 more source

Differential Effects of Donepezil and Tacrine on Recall-Phase Exploration in a Trihexyphenidyl-Induced Cholinergic Impairment Y-Maze Model. [PDF]

Biomedicines
Dragomir AF, Stoleru S, Zugravu A, Poenaru E, Dumitrescu MC, Barbu AC, Fratea S, Stoleru CM, Coman OA, Fulga I.   +9 more
europepmc   +1 more source

L-α-GPC in Cognitive Decline: Mechanisms and Clinical Evidence in Neurodegenerative Disorders. [PDF]

Neuropsychiatr Dis Treat
Putri VA, Hapsari RS, Amalia R.
europepmc   +1 more source