Results 71 to 80 of about 33,915 (216)

The Efficacy of Licensed-Indication Use of Donepezil and Memantine Monotherapies for Treating Behavioural and Psychological Symptoms of Dementia in Patients with Alzheimer’s Disease: Systematic Review and Meta-Analysis

open access: yesDementia and Geriatric Cognitive Disorders Extra, 2011
Background/Aims: Behavioural and psychological symptoms of dementia (BPSD) in Alzheimer’s disease (AD) greatly increase caregiver burden. The abilities of donepezil and memantine to manage BPSD within their licensed indications in AD were compared ...
I.A. Lockhart, M.E. Orme, S.A. Mitchell
doaj   +1 more source

A double-blind placebo-controlled cross-over clinical trial of DONepezil In Posterior cortical atrophy due to underlying Alzheimer's Disease: DONIPAD study. [PDF]

open access: yes, 2018
BACKGROUND: The study investigated whether donepezil exerts symptomatic benefit in patients with posterior cortical atrophy (PCA), an atypical variant of Alzheimer's disease. METHODS: A single-centre, double-blind, placebo-controlled, cross-over clinical
A Burns   +28 more
core   +2 more sources

The Effect of an Early Cognitive Intervention on Global Cognition in Older Hospitalized Adults With Delirium

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Delirium afflicts 17% of older emergency department (ED) patients and 25% of older hospitalized patients. This form of acute brain failure is associated with accelerated cognitive decline. We conducted a randomized controlled trial to determine whether early cognitive intervention improved 4‐month global cognition in older ED ...
Jin H. Han   +15 more
wiley   +1 more source

Upper gastrointestinal bleed associated with cholinesterase inhibitor use [PDF]

open access: yes, 2015
An 86-year-old man was admitted with a 3-day history of melaena and syncope. He was haemodynamically compromised and anaemic on presentation. His only medical history was mild Alzheimer's disease diagnosed 6 months prior. For this, he was on donepezil, a
Kok, Khoon-Sheng   +2 more
core   +1 more source

Association Between Cholinesterase Inhibitor‐Overactive Bladder Antimuscarinic Prescribing Cascade and Risk of Delirium and Falls Among Individuals Living With Dementia

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Prescribing cascades occur when cholinesterase inhibitor (ChEI)‐induced urinary incontinence is misinterpreted as a new condition, leading to overactive bladder (OAB) antimuscarinic initiation. We evaluated whether the ChEI‐OAB antimuscarinic prescribing cascade was associated with delirium or falls compared with mirabegron in older
Sarah Beth Tucker   +9 more
wiley   +1 more source

Does treatment with donepezil improve memory for patients with mild cognitive impairment? [PDF]

open access: yes, 2006
Donepezil (Aricept) has potential benefit in delaying risk of progression to Alzheimer's disease in the first year of treatment, but this benefit is not seen at 3 years.
Martin, Sandra I., Stiles, Melissa M.
core  

Bayesian value-of-infomation analysis: an application to a policy model of Alzheimer's disease [PDF]

open access: yes, 2001
A framework is presented that distinguishes the conceptually separate decisions of which treatment strategy is optimal from the question of whether more information is required to inform this choice in the future.
Araki, S.   +3 more
core   +1 more source

Emergency Departments Leading the Transformation of Alzheimer's and Dementia Care: Emergency Care Redesign

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT Over 50% of persons living with dementia (PLWD) and their care partners (dyads) visit the emergency department (ED) every year. In the ED, healthcare professionals face complex challenges managing acute issues and symptoms of Alzheimer's disease and Alzheimer's disease–related dementias without provider training or in‐ED structures to ensure a
Afshana Hoque   +59 more
wiley   +1 more source

Neuroprotection against vascular dementia after acupuncture combined with donepezil hydrochloride: P300 event related potential

open access: yesNeural Regeneration Research, 2016
Acupuncture can be used to treat various nervous system diseases. Here, 168 vascular dementia patients were orally administered donepezil hydrochloride alone (5 mg/day, once a day for 56 days), or combined with acupuncture at Shenting (DU24), Tianzhu ...
Qiang Liu   +5 more
doaj   +1 more source

Bridging the Gap Between the ED and Home: The Community Paramedic‐Led Transitions Intervention for Persons Living With Dementia

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT More than 6 million persons living with dementia (PLWD) in the United States rely on the emergency department (ED) for unscheduled care, with up to half discharged home after treatment. The ED‐to‐home transition poses significant challenges for PLWD and their care partners (referred to as “dyads”), contributing to high rates of ED revisits and
Meghan Jenkins Morales   +54 more
wiley   +1 more source

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