Results 51 to 60 of about 21,434 (231)
, 2016 Three crystal structures of donepezil salts formed with sulfonic acids were obtained. Interestingly, donepezil-besylate and donepezil-tosylate share similar crystal molecular conformations and crystal packing.
Jae Ho Bae (1669093) +8 more
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Journal of Sleep Research, Volume 34, Issue 2, April 2025.Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont +5 more
wiley +1 more source
Effect of oral donepezil on intraocular pressure in normotensive Alzheimer patients
, 2006 Donepezil, a selective acetylcholinesterase (AChE) inhibitor, has been shown to reduce intraocular pressure (IOP) in ocular normotensive rabbit eyes. The aim of this investigation was to evaluate the effect of oral donepezil on IOP and pupil diameter ...
Estermann, Stephan +5 more
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Psychiatry and Clinical Neurosciences, EarlyView.Aim To determine the smallest worthwhile difference (SWD) for lecanemab, a disease‐modifying drug for Alzheimer's disease (AD), among the general Japanese population using a benefit‐harm trade‐off method. Methods We conducted an online survey with 658 participants to evaluate their preferences for the treatment effect of lecanemab, given its associated
Aran Tajika +5 more
wiley +1 more source
Violent behavior associated with donepezil
, 1998 Reports a case of violent behavior following the commencement of donepezil in a 76-yr-old male with a 2-yr history of cognitive impairment, diagnosed as Alzheimer's disease. Five days after donepezil, 5 mg daily, the S became paranoid, and beat his wife.
Pinner, Gill, Bouman, Walter P.
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Donepezil, anti-Alzheimer's disease drug, prevents cardiac rupture during acute phase of myocardial infarction in mice. [PDF]
PLoS ONE, 2011 BACKGROUND: We have previously demonstrated that the chronic intervention in the cholinergic system by donepezil, an acetylcholinesterase inhibitor, plays a beneficial role in suppressing long-term cardiac remodeling after myocardial infarction (MI).
Mikihiko Arikawa +4 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend A study described in this paper describes a new tool for hiPSC‐CM electromechanical behaviour simulations using mathematical modelling. The model enables in silico assays making drug testing quick, comprehensive and accurate. New hiPSC‐CM models can be used as a platform to integrate in vitro and in silico findings.
Milda Folkmanaite +9 more
wiley +1 more source
, 2019 Background. Although several medical interventions have been used to reduce the cognitive side effects of electroconvulsive therapy (ECT), no specific drug has been yet identified to solve this problem. Objectives.
Nazarinasab, Masoumeh +5 more
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The Journal of Physiology, EarlyView.Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Daisuke Sato +3 more
wiley +1 more source
Neuroprotective effects of donepezil against cholinergic depletion [PDF]
, 2013 Introduction: Intraparenchymal injections of the immunotoxin 192-IgG-saporin into medial septum and nucleus basalis magnocellularis causes a selective depletion of basal forebrain cholinergic neurons.
Anna Maria Tartaglione +16 more
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